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(1)
By Target- Cytochromes P450
- FLAP(1)
- LTR(1)
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Results for "
am679
" in TargetMol Product Catalog- Inhibitors & Agonists1
AM679
AM-679, AM 679
T142051206880-66-1
AM679 is a potent and selective FLAP inhibitor with IC₅₀ values of 2.2 nM (FLAP binding), 0.6 nM (hLA), and 154 nM (hWB). AM679 displays improved CYP inhibition characteristics, no CYP3A4 time-dependent inhibition or induction, and strong in vivo leukotriene inhibition in rodent BAL models after oral administration.
- $71
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