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am679

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
  • AM679
    AM-679, AM 679
    T142051206880-66-1
    AM679 is a potent and selective FLAP inhibitor with IC₅₀ values of 2.2 nM (FLAP binding), 0.6 nM (hLA), and 154 nM (hWB). AM679 displays improved CYP inhibition characteristics, no CYP3A4 time-dependent inhibition or induction, and strong in vivo leukotriene inhibition in rodent BAL models after oral administration.
    • $71
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