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alk/ros-1-in-1

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  • Inhibitors & Agonists
    2
    TargetMol | Inhibitors_Agonists
ALK/ROS1-IN-1
T102862365497-07-8In house
ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
  • $1,520
8-10 weeks
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QTY
PF-06463922 acetate
T700601924207-18-0
PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).
  • $2,420
10-14 weeks
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