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By Tag By Expression System- HEK293 Cells(2)
By Species- Human(2)
By SPR-compatible Buffer- Ready-to-use(2)
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Results for "
ahus 5
" in TargetMol Product Catalog- Recombinant Protein2
CompareHEL-S-62p, CPAMD1, complement component 3, C3b, C3a, ASP, ARMD9, AHUS5
TMPY-05731
Expression system: HEK293 Cells
Length: 1-1663, Full Length
Activity: Not Tested
Length: 1-1663, Full Length
Activity: Not Tested
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SPR-compatible buffer
CompareTRA2.10, TLX, MIC10, MCP, CD46 molecule, complement regulatory protein, AHUS2
TMPY-02023
CD46, also known as Membrane Cofactor Protein (MCP), is a complement regulatory protein. CD46 is a type 1 membrane protein that plays an important inhibitory role in the complement system. CD46 is expressed in white blood cells, platelets, epithelial cells, and fibroblasts. Human CD46 shares 5% amino acid sequence identity with mouse and rat CD46. The importance of CD46 to complement regulation is underscored by the observation that genetic loss of CD46 leads to development of atypical hemolytic-uremic syndrome (aHUS), a disease characterized by uncontrolled complement activation. CD46 is implicated in the development and or progression of selected cancer types.
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