agonistic — TargetMol Chemicals

Cat No.	Product Name	Synonyms	Targets
T23101	O-3M3FBS		Others
	Inactive analog of m-3M3FBS (PLC activator)		Others
T3188	RE-640		CCR , Parasite
	NSC-5844 (RE-640) (RE640) is a bisquinoline compound with C-C chemokine receptor type 1 (CCR1)-agonistic activities.		CCR , Parasite
T9901A-006	Vonlerolizumab	Pogalizumab,RG 7888,MOXR 0916	Others
	Vonlerolizumab(MOXR 0916) is a humanized IgG agonistic OX40-specific monoclonal antibody with potential antitumor activity for the study of tumors and immune diseases.		Others
T8984	FLTX1		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
	FLTX1 is a fluorescent derivative of Tamoxifen, designed to efficiently target and label intracellular Tamoxifen-binding sites (estrogen receptors) both under permeabilized and non-permeabilized conditions. Additionally,...		Estrogen Receptor/ERR , Estrogen/progestogen Receptor
T60124	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea		TNF
	1-(4-chloro-3-(trifluoromethyl)phenyl)-3-(7-(1-methyl-1H-pyrazol-4-yl)-2,3,4,9-tetrahydro-1H-carbazol-3-yl)urea, a TNF-α agonistic compound, could induce cells to secrete TNF- α.		TNF
T61518	TAK-653		iGluR
	TAK-653, a selective positive allosteric modulator (PAM) of AMPA receptors exhibiting minimal agonistic activity, elicits an antidepressant-like response while maintaining a favorable safety profile in rat models.		iGluR
T8779	HBT1		GluR
	HBT1 is an AMPA receptor potentiator that induces production of brain-derived neurotrophic factor (BDNF) and exhibits little agonistic effect in primary neurons. HBT1 binds to ligand-binding domain of AMPA-R in glutamate...		GluR
T0371	Gliquidone	AR-DF 26,Glurenorm	Potassium Channel
	Gliquidone (AR-DF 26) is a potent, second-generation sulfonylurea with antihyperglycemic activity. Like other second-generation compounds, gliquidone exerts greater binding affinity to SUR1 and increased potency compared...		Potassium Channel
T60325	Viloxazine	Emovit,Viloxazin	5-HT Receptor , Norepinephrine
	Viloxazine (Viloxazin) (Viloxazin) is a dual-action compound that functions as a norepinephrine reuptake inhibitor and exhibits potent agonistic activity towards 5-HT 2C receptors while acting as an antagonist for 5-HT 2...		5-HT Receptor , Norepinephrine
T0093L	Sorafenib	Bay 43-9006	Apoptosis , Raf , VEGFR , FLT , Ferroptosis , PDGFR , c-Kit , Autophagy
	Sorafenib (Bay 43-9006) is a multikinase inhibitor that inhibits Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6/22/90/15/20/20/57/58 nM) with oral activity. Sorafenib has antitumor activity...
TP1541L	BDC2.5 mimotope 1040-31 acetate	BDC2.5 mimotope 1040-31 acetate(329696-49-3 free base)	Others
	BDC2.5 mimotope 1040-31 acetate is a effectively agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5. It can stimulate BDC2.5 cells with cells showing good response to this mimotope. 1040-31 peptide is spec...		Others
T6602	Naratriptan hydrochloride	Naratriptan HCl,Amerge,Naramig,GR-85548A hydrochloride	5-HT Receptor
	Naratriptan Hydrochloride is the hydrochloride salt form of naratriptan, a sulfonamide with selective serotonin (5-HT) 1 receptor agonistic activity and anti-migraine property. Naratriptan hydrochloride (GR-85548A hydroc...		5-HT Receptor
T69157	H 160-51
	H 160-51 is a calcium agonistic 1,4-dihydropyridine.
T13461	(+)-Cloprostenol	D-Cloprostenol	Others
	(+)-Cloprostenol is a analogue of prostaglandin F2α (PGF2α), and is selective prostaglandin receptor agonistic.		Others
T69116	Agroclavine
	Agroclavine is a clavine type of ergot alkaloid with D1 dopamine and a-adrenoceptor agonistic properties.
T17292	ZK159222		Others
	ZK159222 is an effective 1α,25-(OH)2D3 receptor (VDR) agonist. ZK159222 has a partial agonistic character.		Others
T15256	Etofylline clofibrate		Others
	Etofylline clofibrate has a hypolipidemic and antithrombotic effect and it also has an agonistic interaction with intimal PGI2.		Others
TP1601	BDC2.5 mimotope 1040-31 TFA(329696-49-3 free base)	BDC2.5 mimotope 1040-31 TFA
	This is a strongly agonistic peptide (mimotope) for diabetogenic T cell clone BDC2.5.
T35834	(Sar1)-Angiotensin II	(Sar¹)-Angiotensin II
	The substitution with Sar at position 1 of angiotensin II resulted in a partial agonistic activity.
T14361	Axomadol	EN3324	Others
	Axomadol (EN3324) is a centrally active analgesic compound. It has opioid agonistic properties and inhibitory effects on the reuptake of monoamines.		Others