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af 219

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
Gefapixant citrate
MK-7264 citrate, AF-219 citrate, RO4926219 citrate, AF219 citrate, MK7264 citrate, RO 4926219 citrate
T638462310299-91-1
Gefapixant citrate (AF-219 citrate) is an orally available, highly potent P2X3 receptor antagonist with antitussive properties that inhibits hP2X2 3. It can be used to study chronic cough.
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1-2 weeks
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Gefapixant
RO 4926219, MK-7264, AF219
T50991015787-98-0
Gefapixant (AF219) is a P2X3 receptor (P2X3R) antagonist with IC50 of ~30 nM at recombinant hP2X3 homotrimers and 100-250 nM at hP2X2 3 heterotrimeric receptors.
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