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act 672125

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
ACT-672125
T706161449367-94-5
ACT-672125 is a Potent CXCR3 Antagonist with Therapeutic Potential in Autoimmune Diseases. ACT-672125 showed good physicochemical properties and safety profile. In a proof-of-mechanism model of lung inflammation, ACT-672125 inhibited the recruitment of CXCR3 expressing T cells into the inflamed lung in a dose-dependent manner.
  • $2,420
10-14 weeks
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Iso-SLR 080811
Iso-SLR080811, 1-Pyrrolidinecarboximidamide, 2-[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]-, hydrochloride (1:1), (2R)-, (2R)-2-[3-(4-octylphenyl)-1,2,4-oxadiazol-5-yl]pyrrolidine-1-carboximidamide hydrochloride
T706141449768-36-8
Iso-SLR 080811 is an isomer of SLR 080811, suitable for relevant research in the life sciences. SLR080811 is a selective SphK2 inhibitor (Ki=1.3 μM) that elevates blood S1P levels in wild-type mice, reduces S1P levels in sphk1 knockout mice, and leaves S1P levels unchanged in SphK2 knockout mice.
  • $293
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