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acid-sensing ion channel (asic)

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  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
A-317567
T14070371217-32-2
A-317567 is a potent acid-sensing ion channel 3 (ASIC-3) inhibitor with an IC50 of 1.025 μM, exhibiting antidepressant and antinociceptive effects[1][2].
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3-6 months
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GMQ hydrochloride
NSC 403387 hydrochloride
T86175361-15-9
GMQ hydrochloride (NSC-403387 hydrochloride) is a potent and selective acid-sensing ion channel (ASIC) modulator. It activates ASIC3 channels under neutral pH and blocks acid-induced maximal peak current.
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ASIC-IN-1
T61537308088-10-0
ASIC-IN-1 is a potent inhibitor of acid-sensing ion channels, demonstrating an IC50 value of less than 10 μM, and it effectively reduces pain intensity in a dose-dependent manner [1].
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6-8 weeks
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