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Results for "
ac-ryyrik-nh-2
" in TargetMol Product Catalog- Inhibitors & Agonists2
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Ac-RYYRIK-NH2
TP1940200959-48-4
High affinity ligand for the NOP site (Ki = 1.5 nM). Antagonizes nociceptin-stimulated GTP binding in rat brain and the chronotropic effect of nociceptin on rat cardiomyocytes. However, displays potent agonist properties in vivo, inhibiting locomotor acti
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Ac-RYYRIK-NH2 acetate
TP1940L1
Ac-RYYRIK-NH2 acetate is an agonist at nociceptin orphanin FQ(noc OFQ) receptors, affecting spontaneous locomotor activity. Ac-RYYRIK-NH2 acetate is a partial agonist on ORL1 transfected in CHO cells, antagonizes the stimulation of [35S]-GTPgammaS binding to G proteins by noc OFQ in membranes and sections of rat brain.
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