a163

Triaziquone is an alkylating agent that can react with DNA to form intrastrand crosslinks.

A 16316-C is a water soluble basic antibiotic, it is isolated from Streptoverticillium eurocidicus.

The Anti-CEACAM7 Antibody (P3-7B) is a chimeric monoclonal antibody of the mouse IgG1, κ class, targeting CEACAM7 (human origin). Its isotype control is MouseIgG1kappa, Isotype Control.

Lpathomab (LT3015; LT-3000) is a human IgG1 monoclonal antibody (mAb) targeting LPA. It reduces the release of cytokines IL-8 and IL-6 in SKOV3 cells and blocks tumor cell migration triggered by LPA. In Matrigel plug and CNV models, Lpathomab decreases angiogenesis. In the CCI mouse model, it inhibits brain injury. This compound can be utilized for research on brain injury, ovarian cancer, diabetic neuropathy, and spinal cord injury. Recommended isotype control: HumanIgG1kappa, Isotype Control.

ASP-1948 is a human monoclonal antibody targeting NRP1/VEGF165R/CD34. It is capable of reversing the inhibitory effects of regulatory T cells and can be applied in the study of solid tumors.

Sym023 is a human monoclonal antibody (mAb) that targets TIM-3/HAVCR2/CD366. It enhances immune stimulation and exhibits anti-tumor activity, making it a valuable research tool for studies on non-small cell lung cancer, solid tumors, and lymphoma.

Anti-CD27 Antibody (M2191) is a human monoclonal antibody (mAb) targeting TNFRSF7/CD27. It can inhibit the binding of sCD70 to human CD27ECD-Fc. Anti-CD27 Antibody (M2191) is applicable in anti-tumor immunology research. The recommended isotype control is Human IgG1 kappa, Isotype Control.

GSK1995057 is a human monoclonal antibody (mAb) targeting TNFRSF1A. It alleviates pulmonary neutrophilia, the release of inflammatory cytokines, and signs of endothelial injury in bronchoalveolar lavage fluid and serum samples. GSK1995057 is used in research on acute lung injury and adult respiratory distress syndrome. The recommended isotype control is dAb (VHH-His).

CC-90006 is a human monoclonal antibody (mAb) targeting PDCD1/PD-1/CD279. It is utilized in psoriasis research. The recommended isotype control for this compound is Human IgG1 kappa, Isotype Control.

ALD1910 is a humanized monoclonal antibody targeting PACAP38 and PACAP27. It inhibits PACAP signaling through pituitary adenylate cyclase-activating peptide type I receptor (PAC1-R), vasoactive intestinal peptide receptor 1 (VPAC1-R), and VPAC2-R. ALD1910 recognizes a non-linear epitope within PACAP and prevents its binding to cell surfaces. It is useful for studying PACAP-mediated migraines.

ADI-65533 is a human IgG1 monoclonal antibody that targets Envelopment polyprotein, M polyprotein. It is useful for research on hantavirus infections. The recommended isotype control is Human IgG1 kappa, Isotype Control.

INCAGN1949 is a human IgG1 monoclonal antibody (mAb) that targets TNFRSF4/OX40/CD134. It selectively depletes regulatory T cells within tumors.

FAZ-053 is a human monoclonal antibody (mAb) that targets B7-H1/PD-L1/CD274. It inhibits the interaction of PD-L1 with PD-1 and B7-1 on monocytes, dendritic cells, and B cells. Additionally, FAZ-053 enhances the production of interleukin-2 and is applicable in research studies on advanced alveolar soft part sarcoma (ASPS), chordoma, and triple-negative breast cancer.