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a1062

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  • Inhibitors & Agonists
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    TargetMol | All_Pathways
  • Inhibitory Antibodies
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    TargetMol | Inhibitory_Antibodies
A-1062
T264621821-13-2
A-1062, a resolvase-binding inhibitor, inhibits resolvase binding to the res site.
  • $1,520
6-8 weeks
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AMG-424
XmAb968
T9901A-1062
AMG-424 (XmAb968) is a human bispecific antibody (bsAb) targeting CD38 and CD3E. It effectively kills cancer cells that express CD38, stimulates T cell proliferation, and reduces cytokine release. AMG-424 exhibits antitumor activity in mouse cancer models with bone marrow invasion and induces peripheral B cell depletion in cynomolgus monkeys. It is used in studies of multiple myeloma. Recommended isotype control: half-IG G1-kappa/(scFv-heavy-lambda)-h-CH2-CH3.
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