T7421

Melperone, a butyrophenone tranquillizer, caused bradycardia in vivo and in vitro.

HIV-1 inhibitor-11 [a fused pyridine ring derivative] is an HIV-1 inhibitor.

HIV-1 inhibitor-12 is a potent inhibitor that targets the HIV-1 capsid protein, effectively preventing its polymerization with an inhibition concentration (IC 50) of 9 nM.

BLT2 Probe 1 (Compound 13), a fluorescent probe derived from the synthetic BLT2 agonist CAY10583, offers a robust tool for exploring BLT2 receptor ligand pharmacology across various assay systems [1]. As BLT2 is a valuable target for treatments in diabetic wound healing and gastrointestinal lesions, this probe facilitates relevant biomedical research.

BAY-6672 hydrochloride is a potent, selective antagonist of the human Prostaglandin F (FP) receptor, exhibiting an IC50 value of 11 nM.

OI338 is an orally available, ultralong-acting insulin analogue (OBOA, UAIA).

EGFR-IN-22 is a highly effective inhibitor targeting wild type EGFR and its mutant form, EGFR L858R/T790M/C797S, displaying IC50 values of 4.91 nM and 0.54 nM, respectively.

Angiogenesis Agent 1 (Compound C-31), a glycoside analogue derived from salidroside, acts as an activator of the HIF-1α pathway and shows potential in diabetic hind limb ischemia research [1].

Maximiscin, a metabolite derived from fungi, causes DNA damage and exhibits selective cytotoxic activity towards a specific subtype of triple-negative breast cancer.