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(1)
By Target- Apoptosis
- CDK(1)
- GSK-3(1)
- Nrf2(1)
- Others(1)
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Results for "
T6940
" in TargetMol Product Catalog.- Inhibitors & Agonists2
PHA-767491 hydrochloride
PHA-767491 HCl, PHA767491 HCl, CAY-10572 hydrochloride, CAY10572 HCl
T6940942425-68-5
PHA-767491 hydrochloride (CAY-10572 hydrochloride) is an effective ATP-competitive dual Cdc7/CDK9 inhibitor (IC50: 10/34 nM). It has ~20-fold selectivity against GSK3-β and CDK1/2, 50-fold selectivity against CDK5 and MK2, 100-fold selectivity against CHK2 and PLK1.
- $43
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MIND4-17
T69401345989-24-4
MIND4-17, a potent NRF2 activator, covalently modifies the C151 residue of Keap1, disrupting the Keap1-Nrf2 association. This action leads to the stabilization and nuclear translocation of the Nrf2 protein, consequently exerting potent antioxidant activity.
- $1,520
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