T6925

P005091 (P5091) is a selective and potent inhibitor of ubiquitin-specific protease 7 (USP7) with EC50 of 4.2 μM.

Ajmalicine (Raubasine) hydrochloride, a potent adrenolytic compound, selectively inhibits α1-adrenoceptors and acts as a reversible, non-competitive full inhibitor of nicotine receptors with an IC50 of 72.3 μM. This chemical also serves as an anti-hypertensive and exhibits sedative activity, making it useful in various therapeutic applications.

ONO-AE1-259 is a highly selective agonist of prostaglandin e2 receptor (ep2)

PPI-2458 is a synthetic derivative of fumagillin with antineoplastic and cytotoxic properties. PPI-2458 irreversibly inhibits the enzyme methionine aminopeptidase type 2 (MetAP2), thereby preventing abnormal cell growth and angiogenesis. PPI-2458 is reported to have a better toxicity profile compared to other agents of its class.