T2658

BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3.

AK301 is a potent and selective inhibitor of tubulin polymerization and an effective sensitizer of cancer cells to apoptotic ligands (EC50 < 200 nM). Colon cancer cells arrested in mitosis with AK301 readily underwent a p53-dependent apoptosis following compound withdrawal and arrest release.

AIC-292 is a potent reverse transcriptase inhibitor with well tolerated in different cell lines. In addition, activity of AIC292 could be demonstrated against a broad panel of wild-type HIV-1 group. AIC292 also retained activity against viruses harboring

AJS1669, an activator of muscle glycogen synthase, improves glucose metabolism and reduces body fat mass in mice.

Alazopeptin is an antitumor antibiotic. It has trypanocidal properties.

Albicidin is a DNA gyrase inhibitor produced by Xanthomonas albilineans.