T2398

Tofacitinib Citrate (CP-690550 citrate) is a a potent, cell-permeable inhibitor of JAK1/2/3 (IC50s: 1/20/112 nM).

Deutetrabenazine metabolite M4 is believed to be related to its effect as a reversible depletion of monoamines from nerve terminals. The major circulating metabolites of Deutetrabenazine, are reversible inhibitors of VMAT2, resulting in decreased uptake

Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

Dextramycine is an optic isomer of chloramphenicol.

Dezinamide is a potential antiepileptic drug. It shows preliminary evidence of efficacy and safety in an open-label study.

DI-404 is a high-Affinity Peptidomimetic the DCN1-UBC12 Protein-Protein Interaction inhibitor (Kd= 6.9 nM). DI-404 effectively and selectively inhibits the neddylation of cullin 3 over other cullin members.