T21588

Olomoucine is an ATP-competitive inhibitor of Cdk2/cyclin A, Cdc2/CyclinB, CDK2/CyclinE, CDK5/p35, and ERK1/p44 MAP kinase with IC50s of 7, 7, 7, 3, and 25 µM, respectively. It regulates the cell cycle and exhibits anti-melanin tumor activities.

tert-Butyl 2-(2-aminoethyl)-2,7-diazaspiro[3.5]nonane-7-carboxylate (dihydrochloride) serves as a PROTAC linker, applicable in synthesizing PROTAC molecules.

CRBN ligand-221 is a ligand for the E3 ubiquitin ligase cereblon (CRBN), utilized for recruiting cereblon proteins. It can be linked through a linker to a target protein ligand to form a PROTAC.

1-(4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenyl)piperazine is a PROTAC linker employed in the synthesis of PROTAC molecules.

tert-Butyl 4-(prop-2-yn-1-yl)piperazine-1-carboxylate is a PROTAC linker used in the synthesis of PROTAC molecules.

CRBN ligand-508 is an E3 ubiquitin ligase cereblon (CRBN) ligand designed to recruit the cereblon protein. It can be linked to a target protein ligand via a linker to form a PROTAC.

Undecane-1,11-diol (1,11-Undecanediol) is a PROTAC linker utilized in the synthesis of PROTAC molecules.

CRBN ligand-529 is an E3 ubiquitin ligase cereblon (CRBN) ligand utilized for recruiting the cereblon protein. Through the use of a linker, CRBN ligand-529 can be attached to a target protein ligand to form a PROTAC.

CRBN ligand-262 is a ligand for the E3 ubiquitin ligase cereblon (CRBN) and is used to recruit cereblon proteins. By utilizing a linker, CRBN ligand-262 can be connected to a target protein ligand to form a PROTAC.

Desamino lenalidomide-6-propyne is an E3 ubiquitin ligase cereblon (CRBN) ligand utilized for recruiting cereblon protein. It can be linked to target protein ligands via a linker to form PROTAC.

4-Chlorobutanal is a PROTAC linker used in the synthesis of PROTAC molecules.