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(2)
By Target- Histone Methyltransferase
- Apoptosis(1)
- Interleukin(1)
- NF-κB(1)
- TNF(1)
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By Target By ResearchField- Cancer(2)
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Results for "
MM102
" in TargetMol Product Catalog.- Inhibitors & Agonists2
- MM-102MM102, HMTase Inhibitor IXT63331417329-24-8MM-102 (HMTase Inhibitor IX) is a potent inhibitor of WDR5/MLL interaction with IC50 of 2.4 nM and Ki of less than 1 nM in a WDR5 binding assay. MM-102 can also specifically inhibit cell growth and induce apoptosis in leukemia cells carrying MLL1 fusion protein.
- $33
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Cited - MM-102 TFAHMTase Inhibitor IX TFAT87681883545-52-5MM-102 TFA (HMTase Inhibitor IX TFA) is a potent WDR5/MLL interaction inhibitor with an IC50 of 2.4 nM. This compound prevents the interaction between mixed lineage leukemia 1 (MLL1) and WD Trp-Asp repeat domain 5 (WDR5), inhibiting MLL1 H3K4 histone methyltransferase (HMT) activity and down-regulating H3K4me3, which facilitates the epigenetic reprogramming of porcine somatic cell nuclear transfer embryos.
- $33
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