Fritillaria

Yibeinoside A (Sinpeinine-3-O-β-glucoside) is an alkaloid from Fritillaria pallidiflora.

Kauran-16,17-diol, a natural diterpenoid product, exhibits anti-tumoral and apoptosis-inducing activities by inhibiting NO production in LPS-induced RAW 264.7 cells with an IC50 value of 17 μM.

Ebeiedinone, a steroidal alkaloid derived from Fritillaria species, effectively inhibits the activity of human whole blood cholinesterase (ChE) at a concentration of 0.1 mM, resulting in a significant inhibitory effect of 69.0%.

Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and cholinesterase inhibition.

1. Peimisine (Ebeiensine) can affect M-receptor, excit β-receptor, restrain the release of internal calcium, and promote to releaseing nitrogen monoxidum in order to relax tracheal smooth muscle and relieve asthma. 2. Peimisine can attenuate lung tissue injury( ALI), LDH and MDA amount in ALI mice in a dose dependent manner, it also lower the total protein, total white blood cells, lymphocyte and neutrophilic leukocyte in bronchoalveolar lavage fluid( BALF); suggests that peimisine can play a protective role against LPS-induced acute lung injury. 3. Peimisine has the protective effect on the experimental hepatic fibrosis formation, the possible mechanisms are associated with inhibiting fibrogenesis and fibrosis accumulation, and decreasing lipid peroxidation. 4. Peimisine can inhibit angiotensin I converting enzyme activity in a dose-dependent manner, displaying 5 % inhibitory concentration values of 526.5 microM, thus, it may have antihypertensive action.

1. Peiminine (Raddeanine) is an effective inhibitor for lung inflammation and pulmonary fibrosis in a rat model of bleomycin-induced lung injury.

1. Peimine (Wanpeinine A) has good anti-inflammatory effects in vivo. 2. Peimine is an inhibitor to inhibit LPS-induced production of inflammatory cytokines by blocking the MAPKs and NF-κB signaling pathway.

1. Sipeimine (Kashmirine) has antiasthmatic effect, on tracheal M receptor antagonist. 2. Sipeimine can make Kaba cholinergic induced contraction of tracheal strips of the dose-response curve to the right.

Peimisine 3-O-β-D-glucopyranoside is a steroidal alkaloid isolated from the bulb of Monocarpus monocarpus with partial neuroprotective activity, and can be used for the study of rotenone-induced neurotoxicity in the PC12 cell line.

Inosine (Standard) is a reference standard for inosine, suitable for quantitative analysis, quality control, and biochemical experiments. Inosine is an endogenous purine nucleoside produced by the catabolism of adenosine. It acts as an agonist for adenosine receptors and can be used in studies of inflammation, immunity, and neuroprotection.

Hupehenine (Standard) is a reference standard for research and analysis in studies involving Hupehenine. Hupehenine is a steriodal alkaloid extracted from the bulbs of Fritillaria Hupehensis, with the potential for inhibiting acetylcholine, antagonism for muscarinic receptors and cholinesterase inhibition.

Isoverticine exhibits significant antitussive, expectorant and anti-inflammatory activities, it also displays significant cytotoxicity.

Imperialine 3-β-D-glucoside (Sipeimine-3-beta-D-glucoside) is a natural product. Imperialine 3-β-D-glucoside may exhibit anti-tumor properties against multi-drug resistant tumor cells.

Pingpeimine A has the effect of expectorating and lowering blood pressure. Derived from Fritillaria sibiricum.

Pingpeimine B Derived from Fritillaria sibiricum.

Pingpeimine C Derived from Fritillaria sibiricum.

Yibeissine is a natural steroidal alkaloid isolated from the bulb of Fritillaria pallioiflora Schren.