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Search Results for " ep1 "

20

Compounds

Cat No. Product Name Synonyms Targets
T10031 EP1-antagonist-1 EP1-antanoist-1,EP1 antagonist 1 Prostaglandin Receptor
EP1-antagonist-1 (EP1 antagonist 1) is an EP1 antagonist (pKi: 7.54; pIC50: 8.5).
T5841 Travoprost Flu-Ipr,Fluprostenol isopropyl ester,AL6221 Prostaglandin Receptor
Travoprost (Fluprostenol isopropyl ester) is used to treat glaucoma and ocular hypertension,is a potent and selective FP prostaglandin receptor agonist.
T1626 Prostaglandin E1 PGE1,Alprostadil Endogenous Metabolite , Prostaglandin Receptor
Prostaglandin E1 (Alprostadil) is the naturally occurring prostaglandin E1 (PGE1) which displays a variety of pharmacologic actions. Prostaglandin E1 is a potent vasodilator agent that increases peripheral blood flow, in...
T76273 Pep19-2.5
Pep19-2.5, a synthetic antitoxin peptide, inhibits the intracellular signaling cascade triggered by endotoxins by blocking the activity of lipopeptides (LP) and lipopolysaccharides (LPS) mediated through both transmembra...
TP2196 Pep1-AGL Others
Analog of Pep1-TGL
TP2197 Pep1-TGL Others
Peptide containing the 'TGL' motif that corresponds to the C-terminus of GluR1 subunit
T11210 EP1013 F1013 Caspase
EP1013 is a broad-spectrum selective inhibitor of Caspase used in the study of type 1 diabetes.
T78846 EP12 Apoptosis
EP12, a c-Myc inhibitor and G4 stabilizer, induces apoptosis and DNA damage in multiple myeloma cells while obstructing P65/P50 nuclear translocation by disrupting the NF-κB signaling pathway, effectively inhibiting mult...
T74445 ZA3-Ep10
ZA3-Ep10, a zwitterionic lipid, is utilized in the formulation of lipid nanoparticles for RNA delivery in vivo and non-viral CRISPR/Cas gene editing applications.
T80418 TAT-NEP1-40 Apoptosis
TAT-NEP1-40, a blood-brain barrier (BBB) permeable peptide, confers protection to PC12 cells against oxygen and glucose deprivation (OGD) while promoting neurite outgrowth. Furthermore, it enhances neurologic outcomes po...
T81517 PEP1
PEP1 is a biologically active peptide that interacts with POPC supported lipid bilayers (SLBs), binding at low concentrations, while higher concentrations induce POPC SLB lysis.
T80419 TAT-NEP1-40 TFA Apoptosis
TAT-NEP1-40 TFA, a blood-brain barrier-permeable peptide, safeguards PC12 cells against oxygen and glucose deprivation (OGD) and fosters neurite outgrowth. Additionally, it enhances neurological outcomes post-ischemia by...
T80420 TAT-NEP1-40 acetate Apoptosis
TAT-NEP1-40 acetate, a potential therapeutic for axonal regeneration and functional recovery post-stroke, safeguards PC12 cells from oxygen and glucose deprivation (OGD) and encourages neurite outgrowth. This compound al...
T14148 AH 6809 Prostaglandin Receptor
AH 6809 is an antagonist of EP and DP receptor(with Kis of 1217, 1150, 1597, and 1415 nM for the cloned human EP1, EP2, EP3-III, and DP receptor respectively). AH 6809 has a Ki of 350 nM for mouse EP2 receptor.
T21976 ONO-8130 Prostaglandin Receptor
ONO-8130 is an orally available antagonist of EP1 receptor.
T63667 ONO-8713 Prostaglandin Receptor
ONO-8713 is a selective prostaglandin E receptor subtype EP1 antagonist that can be used to study diseases of the biblical system and metabolism-related diseases.
T14975 CJ-42794 CJ-042794 Others
CJ-42794 (CJ-042794) is a selective antagonist of prostaglandin E receptor subtype 4 (EP4). It inhibits [3H]-PGE2 binding to the human EP4 receptor (a mean pKi: 8.5). CJ-42794 is a binding affinity that was at least 200-...
T11211 EP4 receptor antagonist 1 Prostaglandin Receptor
EP4 Receptor Antagonist 1 is a highly potent and selective competitive prostanoid EP4 receptor antagonist, effective for cancer immunotherapy. It inhibits both human and mouse EP4 receptors with IC50 values of 6.1 nM and...
T63349 Treprostinil diethanolamine UT-15C Prostaglandin Receptor
Treprostinil diethanolamine (UT-15C) is a potent agonist of EP2, DP1 and IP, with values of 3.6, 4.4, 32.1, 212, 826, 2505 and 4680 nM for EP2, DP1, IP, EP1, EP4, EP3 and FPKi, respectively. Treprostinil diethanolamine i...
T3306 PF-04418948 PF 04418948,PF04418948 Prostaglandin Receptor
PF-04418948 is a potent EP2 receptor antagonist (IC50 = 16 nM for human EP2 receptors). Displays over 2000-fold selectivity for EP2 receptors over EP1, EP3, EP4, DP1 amd CRTH2 receptors; exhibits <30% binding at a divers...
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