Crotaline

Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid extracted from the seeds of Crotalaria plants. It inhibits organic cation transporters OCT-1 and OCT-2, with IC50 values of 36.8 µM and 1.8 mM, respectively. Monocrotaline exhibits antitumor activity and shows certain cytotoxicity against liver cancer cells such as HepG2. It is also commonly used to induce pulmonary arterial hypertension models in rodents.

Dicrotaline is a useful organic compound for research related to life sciences and the catalog number is T124802.

Monocrotaline N-Oxide is a monocrotaline metabolite.

Monocrotaline N-Oxide (Standard) is a reference standard for research and analysis in studies involving Monocrotaline N-Oxide. Monocrotaline N-Oxide is a monocrotaline metabolite.

Monocrotaline (Standard) is a reference standard for research and analysis in studies involving Monocrotaline. Monocrotaline is an 11-membered macrocyclic pyrrolizidine alkaloid extracted from the seeds of Crotalaria plants. It inhibits organic cation transporters OCT-1 and OCT-2, with IC50 values of 36.8 µM and 1.8 mM, respectively. Monocrotaline exhibits antitumor activity and shows certain cytotoxicity against liver cancer cells such as HepG2. It is also commonly used to induce pulmonary arterial hypertension models in rodents.

Dehydromonocrotaline (Monocrotaline pyrrole) is a metabolite of Monocrotaline. It acts as an alkylating agent, capable of reacting with DNA, exhibiting cytotoxicity, and causing damage to both the liver and lungs.