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1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE), a phospholipid member of the glycerophosphonoethanolamine family, is a major component in biological membranes. Studies have shown that cholesterol induces condensation of DPPE monolayers in the presence of Ca2+ ions, leading to more ordered lipid tails and resulting in a thicker membrane.

(S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) is a phosphatidylethanolamine lipid composed of two palmitoyl chains. As a chiral isomer, (S)-1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (DPPE) exhibits amphiphilic properties under physiological conditions and is commonly used to construct liposomes and model biological membrane systems. Its high phase transition temperature enables it to enhance the order and stability of membrane structures, making it highly valuable in membrane fusion research and drug delivery systems.

1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine-D62 is the deuterated form of 1,2-Dipalmitoyl-sn-glycero-3-phosphoethanolamine (T5238). The latter is an endogenous metabolite.