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Results for "

9(z),11(e),13(e)octadecatrienoic acid ethyl ester

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester
T3688842021-86-3
9(Z),11(E),13(E)-Octadecatrienoic Acid ethyl ester (α-ESA) is a conjugated polyunsaturated fatty acid commonly found in plant seed oil. This fatty acid accounts for about 60% of the total fatty acid composition of bitter gourd seed oil and about 70% in tung oil. α-ESA is metabolized and converted to conjugated linoleic acid (9Z,11E-CLA) in rats. It has shown potential as a tumor growth suppressor. In colon cancer Caco-2 cells, α-ESA induced apoptosis through up-regulation of GADD45, p53, and PPARγ. In DLD-1 cells supplemented with α-ESA, apoptosis was induced via lipid peroxidation with an EC50 of 20 μM. It also inhibits DNA polymerases and topoisomerases with IC50s ranging from ~5-20 μM for different isoforms of the enzymes. α-ESA ethyl ester is a neutral, more lipid soluble form of the free acid.
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Citronellol
dihydrogeraniol
T3240106-22-9
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
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Menthyl acetate
L-​Menthyl acetate, (-)-​Menthyl acetate
T80472623-23-6
2'-Deoxycytidine is one of the major nucleosides of DNA consisting of cytosine and deoxyribose and inhibits the biological effects of bromodeoxyuridine (Brdu). The nucleoside consists only of a pentose sugar attached to a purine or pyrimidine base and has no phosphate group. When N1 is attached to C1 of deoxyribose, deoxyribosides and nucleotides are formed from cytosine and deoxyribose; deoxycytidine monophosphate (dCMP), deoxycytidine diphosphate (dCDP), and deoxycytidine triphosphate (dCTP). cTP is the source of cytosine in RNA (ribonucleic acid) and deoxycytidine triphosphate (dCTP) is the source of deoxycytidine in DNA (deoxyribonucleic acid). Itaconic acid is a polymer.
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Myrcene
T5834123-35-3
Myrcene is a terpene that has been found in Cannabis and has antioxidative properties.
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L-Glutamic acid
glutamic acid, glutacid, (S)-Glutamic acid, (+)-L-Glutamic acid
T2A249756-86-0
L-Glutamic acid (Glutaminol) acts as an excitatory transmitter, shows a direct activating effect on the release of DA from dopaminergic terminals.
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Estragole
p-Allylanisole, Methyl chavicol, 4-Allylanisole
T5649140-67-0
Estragole (4-Allylanisole) is found in allspice,and is a constituent of many essential oils. Estragole is a flavouring agent.
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(-)-Isopulegol
Fr1420789-79-2
Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH incr
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(-)-Cedrene
Alpha-Cedrene
T8292469-61-4
(-)-Cedrene (Alpha-Cedrene) is a sesquiterpene from cedar oil that has anti-leukemia, antibacterial and anti-obesity properties.
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Sinapinic Acid
Sinapic acid, Synapoic acid
T3753530-59-6
Sinapinic Acid (Synapoic acid) protects the rat liver from CCl4-induced inflammation, most likely by acting as a free radical scavenger and modulator of NF-κB p65 activation and proinflammatory cytokine expression. Sinapic acid with antioxidant role protects cardiac cells and its functions from I R induced oxidative stress. Sinapic acid is a potentially useful agent for the protection against liver fibrosis and cirrhosis. Sinapic acid prevents the alterations in the levels of lipids and lipoproteins by virtue of its anti-lipidaemic effect in isoproterenol induced myocardial infarcted rats. Sinapic acid ameliorates hyperglycemia through PLC-PKC signals to enhance the glucose utilization in diabetic rats.
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Desaminotyrosine
Phloretate, 3-(4-Hydroxyphenyl)propanoic acid, Hydro-p-coumaric acid, 3-(4-Hydroxyphenyl)propionic acid, Phloretic acid
T2862501-97-3
Desaminotyrosine (3-(4-Hydroxyphenyl)propionic acid) is a microbially associated metabolite. Desaminotyrosine protects from influenza through augmentation of type I interferon signaling.
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Emodin
Frangula emodin
T2869518-82-1
Emodin (Frangula emodin) is a naturally occurring anthraquinone present in the roots and barks of numerous plants; exerts antiproliferative effects in Y cells that are regulated by different signaling pathways.
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2-Ethylbutyric Acid
T802788-09-5
2-Ethylbutyric acid is an internal standard that can be used in calibration methods for VFA analytical standards for feces.
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Methyl Vanillate
T28183943-74-6
Methyl vanillate is Hovenia Dulcis Thunb extract and its ingredient methyl vanillate activate Wnt β-catenin pathway and increase bone mass in growing or ovariectomized mice. Methyl vanillate is considered to be a slightly soluble (in water) acidic compound. Methyl vanillate can be synthesized from vanillic acid. Methyl vanillate has been identified in foods such as cow's milk and beer.
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Cedrol
T559477-53-2
Cedrol is a cedrane sesquiterpenoid and a tertiary alcohol,Cedrol inhibits the cytochrome P450 (CYP) isoforms CYP2B6 and CYP3A4 (Kis = 0.9 and 3.4 μM, respectively)
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DL-alpha-Tocopherol
DL-α-Tocopherol, Alpha-Tochopherol, Ephanyl
TMA239410191-41-0
DL-alpha-Tocopherol (Ephanyl) is a synthetic vitamin E that protects skin fibroblasts from the cytotoxic effects of UV light and has antioxidant properties.
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Mangiferin
Alpizarin, Chinomin, Hedysarid
T30124773-96-0
Mangiferin (Hedysarid) is used for antidiabetes. Extracted from Mangifera indica L.
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Benzamide
Amid kyseliny benzoove, Phenylcarboxyamide, Benzoylamide
T678055-21-0
Benzamide (Amid kyseliny benzoove), an inhibitor of poly(ADP-ribose) polymerase, is a derivative of benzoic acid.
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Citral
alpha-Citral
T31545392-40-5
Citral A monoterpene, obtained from the essential oil of lemongrass, which has anti-pain and anti-inflammatory properties.
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Citronellyl acetate
T8057150-84-5
Citronellyl acetate is a natural product
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Vitamin K1
Phytonadione, Phytomenadione, Phylloquinone, Phyllohydroquinone
T107584-80-0
Vitamin K1 (Phylloquinone) a fat-soluble, naturally occurring vitamin with antihemorrhagic and prothrombogenic activity.
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Eicosane
TN6992112-95-8
Eicosane is a natural product.
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Octacosanoic acid
T8121506-48-9
Octacosanoic acid has antiplatelet and antithrombotic effects.
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Betulin
Trochol, Betulol, betulinol, betulinic alcohol, betuline
T3121473-98-3
Betulin (betulinol) (lup-20(29)-ene-3β, 28-diol) is an abundant, naturally occurring triterpene. It is commonly isolated from the bark of birch trees where it forms up to 30% of the dry weight of the extractive and is found in birch sap as well.
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L-Lysine
Aminutrin, Lysine Acid, lysine
T2A249856-87-1
L-Lysine (Aminutrin) is one of nine essential amino acids in humans required for growth and tissue repair, Lysine is supplied by many foods, especially red meats, fish, and dairy products. Lysine seems to be active against herpes simplex viruses and present in many forms of diet supplements. The mechanism underlying this effect is based on the viral need for amino acid arginine; lysine competes with arginine for absorption and entry into cells. Lysine inhibits HSV growth by knocking out arginine.
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