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854107-55-4

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  • Ponesimod-D7
    TMID-0871
    Ponesimod-D7 is the deuterium-labeled form of Ponesimod (T3258). It is an effective, selective, and orally active agonist of S1P1, with an IC50 value of 6 nM in radioligand binding assays. Ponesimod-D7 efficiently activates S1P1-mediated signal transduction with an EC50 of 5.7 nM and can prevent lymphocyte-mediated tissue inflammation.
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