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8 dehydrocholesterol

" in TargetMol Product Catalog
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8-Dehydrocholesterol
T1916470741-38-7
8-Dehydrocholesterol is a compound whose elevated concentration is a diagnostic biochemical hallmark of classical Smith-Lemli-Opitz syndrome.
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    8(14)-Dehydrocholesterol
    TYD-04416177962-82-2
    8(14)-Dehydrocholesterol is classified as a sterol.
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    10-14 weeks
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    AY 9944
    T14362366-93-8In house
    AY 9944 is a specific cholesterol biosynthesis inhibitor that targets the 7-dehydrocholesterol Δ7-reductase (DHCR7) enzyme (IC50=13 nM). At high doses, AY 9944 also inhibits sterol Δ7-Δ8 isomerase in cultured embryos, leading to the accumulation of cholest-8-en-3β-ol[1][2][3]. Additionally, AY 9944 causes hypocholesterolemia and accumulation of 7DHC.
    • $35
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