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Results for "

7octynoic acid

" in TargetMol Product Catalog
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7-Octynoic acid
T1734510297-09-3
7-Octynoic acid (compound 42) serves as a PROTAC linker for synthesizing various PROTACs, composed of two distinct ligands joined by this linker, where one ligand interacts with an E3 ubiquitin ligase and the other binds to the target protein, leveraging the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
  • Inquiry Price
7-10 days
Size
QTY
FKBP12 PROTAC dTAG-7
T112922064175-32-0In house
FKBP12 PROTAC dTAG-7 (dTAG-7) is a heterobifunctional compound that selectively degrades the BET bromodomain transcriptional co-activator BRD4 by linking BET bromodomains to the E3 ubiquitin ligase CRBN. It also functions as a degrader of FKBP12F36V when FKBP12F36V is expressed in-frame with a targeted protein.
  • TBD
35 days
Size
QTY
(Iso)-MS4322
YS43-22 (isomer), MS4322 (isomer), (Iso)-YS43-22
T402332601727-80-2In house
(Iso)-MS4322 ((Iso)-YS43-22) is a selective and potent protein arginine methyltransferase 5 (PRMT5) degrader with potential anticancer activity that effectively reduces PRMT5 protein levels in MCF-7 cells and inhibits the growth of a wide range of cancer cells.
  • $489 TargetMol
In Stock
Size
QTY
Boc-NH-PEG7-NH2
T14756206265-98-7
Boc-NH-PEG7-NH2 is a PEG-based PROTAC linker.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Bis-Tos-PEG7
T1763669502-27-8
Bis-Tos-PEG7 is a PEG-based PROTAC linker used in PROTAC synthesis.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
Boc-NH-PEG7-Tos
t-Boc-N-Amido-PEG7-Tos
T176821292268-14-4
Boc-NH-PEG7-Tos (t-Boc-N-Amido-PEG7-Tos) is a PEG-based PROTAC linker that can be used in PROTAC synthesis.
  • $37
In Stock
Size
QTY
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Br-PEG7-Br
T17695177987-04-1
Br-PEG7-Br is a PEG-based PROTAC linker utilized in PROTAC synthesis.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
m-PEG7-alcohol
O-Methyl-heptaethylene glycol
T182144437-01-8
m-PEG7-alcohol (O-Methyl-heptaethylene glycol) is a PEG-based PROTAC linker. m-PEG7-alcohol can be used in the synthesis of PROTACs.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
m-PEG7-Br
T18215104518-25-4
m-PEG7-Br is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
  • $29
In Stock
Size
QTY
TargetMol | Inhibitor Sale
CCR7 Ligand 1
CCR7-Cmp2105
T10716681514-83-0
CCR7 Ligand 1 (CCR7-Cmp2105) is an allosteric ligand and antagonist for human CC chemokine receptor 7 (CCR7) with a Kd of 3 nM. This thiadiazole-dioxide ligand suppresses arrestin binding in response to activation by CCL19 with an IC50 of 7.3 μM.
  • $1,928
10-14 weeks
Size
QTY
(R)-CR8 trihydrochloride
CR8, (R)-Isomer trihydrochloride
T126171786438-30-9
(R)-CR8 trihydrochloride (CR8, (R)-Isomer trihydrochloride) is a CDK1 2 5 7 9 inhibitor that acts as a molecular glue degrader with neuroprotective activity and induces apoptosis.
  • $35
In Stock
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(R)​-​CR8
CR8, (R)-Isomer
T12617L294646-77-8
(R)-CR8 ((R)-Isomer) is a potent and selective CDK inhibitor.
  • $61
In Stock
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QTY
TargetMol | Inhibitor Sale
ERD-308
T136852320561-35-9
ERD-308 induces >95% of ER degradation at concentrations as low as 5 nM in both cell lines (DC50 (concentration causing 50% of protein degradation) of 0.17 nM and 0.43 nM in MCF-7 and T47D ER+ cells, respectively).ERD-308 is a highly potent PROTAC degrade
  • $913
Backorder
Size
QTY
(S,R,S)-AHPC-propargyl
VHL ligand 7,VH032-propargyl
T138762098799-78-9
(S,R,S)-AHPC-propargyl, a VHL ligand, is utilized in click reactions for PROTACs.
  • $83
5 days
Size
QTY
Amino-PEG7-amine
T14248332941-25-0
Amino-PEG7-amine, a PEG-based linker for PROTACs, connects two essential ligands crucial for PROTAC molecule formation and facilitates selective protein degradation via the ubiquitin-proteasome system within cells.
  • Inquiry Price
7-10 days
Size
QTY
Aminooxy-PEG7-methane
T142771370698-27-3
Aminooxy-PEG7-methane is a PEG-based linker for PROTACs, joining two essential ligands to facilitate selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Azide-PEG7-Tos
T143991418561-41-7
Azide-PEG7-Tos is a PEG-based linker for PROTACs that connects two essential ligands, critical for forming PROTAC molecules, and facilitates selective protein degradation by utilizing the ubiquitin-proteasome system within cells.
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Azido-PEG7-alcohol
T144721274892-60-2
Azido-PEG7-alcohol is a PEG-based linker for PROTACs that connects two essential ligands, facilitating the formation of PROTAC molecules and enabling selective protein degradation via the ubiquitin-proteasome system within cells (brackets).
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Azido-PEG7-amine
T144751333154-77-0
Azido-PEG7-amine is a non-cleavable ADC linker and PEG-based PROTAC linker that can be used to synthesise antibody-drug conjugates (ADCs) and PROTACs. It can undergo click chemistry reactions with molecules containing alkyne, DBCO or BCN groups.
  • $42
In Stock
Size
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Biotin-PEG7-azide
T146101334172-75-6
Biotin-PEG7-azide, a PEG-based linker for PROTACs, connects two essential ligands pivotal for PROTAC molecule formation, facilitating selective protein degradation via the ubiquitin-proteasome system within cells.
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Bis-aminooxy-PEG7
T146211383980-52-6
Bis-aminooxy-PEG7, a PEG-based linker for PROTACs, facilitates the formation of PROTAC molecules by joining two essential ligands. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.
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Bis-PEG7-acid
T1464794376-75-7
Bis-PEG7-acid and bis-PEG6-propionic acid are chemical compounds that serve as linkers in the synthesis of PROTACs and antibody-drug conjugates (ADCs), respectively. Bis-PEG7-acid is a PEG-based PROTAC linker, while bis-PEG6-propionic acid is a cleavable ADC linker[1].
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Bis-PEG7-NHS ester
T146481334170-02-3
Bis-PEG7-NHS ester is a cleavable ADC linker utilized in the synthesis of antibody-drug conjugates (ADCs) [1].
  • $36
5 days
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Bis-PEG7-PFP ester
T146491334170-01-2
Bis-PEG7-PFP ester, a PEG-based linker for PROTACs, facilitates the selective degradation of proteins by connecting two essential ligands and utilizing the ubiquitin-proteasome system within cells.
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