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609799-22-6

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  • Tasimelteon-D5
    T700351962124-51-1
    Tasimelteon-D5 is intended for use as an internal standard for the quantification of tasimelteon by GC- or LC-MS. Tasimelteon (T3495) is a melatonin (MT) receptor agonist. It selectively binds MT1 and MT2 receptors over a panel of 160 additional receptors and enzymes at 10 µM. Tasimelteon (T3495) inhibits forskolin-induced cAMP accumulation with EC50 values of 0.79 and 1 nM in NIH3T3 cells expressing the MT1 or MT2 receptor, respectively. Formulations containing tasimelteon have been used in the treatment of non-24-hour sleep-wake disorder.
    • $878
    35 days
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