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Results for "
6-o-desmethyl donepezil
" in TargetMol Product Catalog- Inhibitors & Agonists1
6-O-desmethyl Donepezil
T37360120013-56-1
6-O-desmethyl Donepezil is an active metabolite of the acetylcholinesterase inhibitor donepezil . It is formed through dealkylation by the cytochrome P450 (CYP) isoform CYP2D6. It inhibits human ether a go-go (hERG) channels (IC50 = 1.5 μM in HEK293 cells expressing hERG).
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