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By Target- Cytochromes P450
- Drug Metabolite(1)
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Results for "
6-hydroxy warfarin
" in TargetMol Product Catalog- Inhibitors & Agonists3
- Isotope Products1
6-hydroxy Warfarin
T3672517834-02-5
6-Hydroxywarfarin, a metabolite of (+)-warfarin, acts as a weak vitamin K antagonist.
- $120
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QTY
10-hydroxy Warfarin
T3676983219-99-2
10-hydroxy Warfarin is a metabolite of (R)-warfarin .1It is formed from (R)-warfarin by the cytochrome P450 (CYP) isoform CYP3A4. 10-hydroxy Warfarin is an inhibitor of CYP2C9 (IC50= 1.6 μM), the enzyme that converts (S)-warfarin to its 6-hydroxy warfarin and 7-hydroxy warfarin metabolites.2
1.Kaminsky, L.S., and Zhang, Z.-Y.Human P450 metabolism of warfarinPharmacol. Ther.73(1)67-74(1997) 2.Jones, D.R., Kim, S.-Y., Guderyon, M., et al.Hydroxywarfarin metabolites potently inhibit CYP2C9 metabolism of S-warfarinChem. Res. Toxicol.23(5)939-945(2010)
- $183
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QTY
7-Hydroxy Warfarin-d5
TMIJ-020194820-65-2
7-Hydroxy Warfarin-d5 is a deuterated compound of 7-Hydroxy Warfarin. 7-Hydroxy Warfarin has a CAS number of 17834-03-6.
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