57452-98-9

(R)-Praziquantel is an active enantiomer of praziquantel.

Praziquantel (Standard) is the standard substance of Praziquantel, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.

(S)-Praziquantel is the inactive isomer of R-praziquantel.

Praziquantel-D11 (Standard) is the standard substance of Praziquantel D11, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Praziquantel D11 is the deuterium labeled Praziquantel, and is an agent of anthelmintic.

(R)-Praziquantel-D11 is the deuterium labeled  (R)-Praziquantel (T20127). (R)-Praziquantel is the active enantiomer of Praziquantel, is a partial the human 5-HT2B receptor agonist

(S)-Praziquantel-D11 is a deuterated compound of  (S)-Praziquantel (T206068). (S)-Praziquantel has a CAS number of 57452-97-8.

Praziquantel (Droncit) increases the permeability of the tegument of susceptible worms, resulting in an influx and increase in intra-tegumental calcium leading to rapid contractions and paralysis of the worm's musculature through a subsequent increase in levels of calcium in the sarcoplasmic reticulum. Praziquantel is a pyrazinoisoquinoline derivative with anthelminthic property. In addition, vacuolization of the tegumental syncytium and blebbing results in tegument disintegration, leads to antigen exposure and elicit host defense responses to the worm.