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- Inhibitors & Agonists1
- Peptide Products1
BigLEN(mouse)
BigLEN (mouse)
TP2073501036-69-7
GPR171 agonist. ProSAAS-derived neuropeptide. Regulates food intake in mice. Inhibits the release of glutamate onto parvocellular neurons of the paraventricular nucleus in a process dependent upon activation of postsynaptic G proteins.
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BigLEN (mouse) acetate (501036-69-7 Free base)
TP2073L
BigLEN (mouse) acetate is a potent and selective agonist of orphan G protein-coupled receptor 171 (GPR171), with a Kd of ∼0.5 nM.
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BigLEN (rat)
TP2074369377-66-2
Potent GPR171 agonist (EC50 = 1.6 nM). ProSAAS-derived peptide. Regulates body weight in mice and promotes the outgrowth of neurites in Neuro2A cells.
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