5-methoxyuridine

5-Methoxyuridine (Mo5U) is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.5-Methoxyuridine's anticancer mechanism is dependent on the inhibition of DNA synthesis.5-Methoxyuridine is a purine nucleoside analog with a broad spectrum of antitumor activity, targeting malignant tumors of the inert lymphatic system and inducing apoptosis.

Nucleoside Derivatives - 5-Modified pyrimidine nucleosides, Protected nucleosides with NH2 OH open

3'-Deoxy-3'-fluoro-xylo-5-methoxyuridine is a Nucleoside Derivative - xylo-nucleoside;Fluoro-modified nucleoside; 5-Modified pyrimidine nucleoside.

2'-C-Methyl-5-methoxyuridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

2',3',5'-Tri-O-benzoyl-2'-C-methyl-5-methoxyuridine is a 2'-C-Methyl nucleoside; 5-Modified pyrimidine nucleoside.

Nucleoside Derivatives - 5-Modified nucleosides

5-Methoxyuridine 5'-triphosphate trisodium solution (100mM) is a modified nucleotide triphosphate (NTP). It can be incorporated into mRNA using T7 RNA polymerase.

Nucleoside Derivatives - 3'-Deoxy nucleosides, 5-Modified pyrimidine nucleosides

Nucleoside Derivatives - 5-Modified pyrimidine nucleoside

3'-beta-C-Methyl-5-methoxyuridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside.

Nucleoside Derivatives - Azido-nucleosides, 5-Modified pyrimidine nucleosides, 3'-Modified nucleosides

3'-beta-C-Ethynyl-5-methoxyuridine is a Nucleoside Derivative - 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside.

Nucleoside Derivatives - 4'-Modified nucleosides; 5-Modified pyrimidine nucleosides

2',3',5'-Tri-O-benzoyl-5-methoxyuridine is a 5-Modified Pyrimidine Nucleoside.

5'-O-DMTr-2'-O-TBDMS-5-methoxyuridine-3'-(cyanoethyl-N,N-diisopropyl)phosphoramidite is a Nucleoside Phosphoramidite.

5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.

Erastin is an iron death activator that acts on the mitochondrial VDAC in a ROS- and iron-dependent manner. Erastin has anti-tumor activity and acts selectively on tumor cells with RAS-carcinogenic mutations.

LY294002 (SF 1101) is a broad-spectrum inhibitor of PI3K, inhibiting PI3Kα, PI3Kδ, and PI3Kβ (IC50=0.5 0.57 0.97 μM). LY294002 is also an inhibitor of DNA-PK (IC50=1.4 μM) and an inhibitor of CK2 (IC50=98 nM). LY294002 activates apoptosis and autophagy.

(-)-Epigallocatechin Gallate (EGCG) is a phenolic antioxidant polyphenol flavonoid found in plants such as green and black tea, which inhibits telomerase and DNA methyltransferase, blocks the activation of EGF receptors and HER-2 receptors, inhibits cellular oxidation, and prevents free radical damage to cells.

Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6 15 2 3 3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.

Decitabine (Deoxycytidine) is a deoxycytidine analog, a DNA methyltransferase inhibitor with oral activity. Decitabine has antitumor activity and antimetabolic activity. Decitabine induces cell cycle arrest and apoptosis.

Marimastat (BB2516) (BB-2516) is a potent, broad spectrum matrix metalloprotease (MMP) inhibitor. MMP-9 (IC50=3 nM), MMP-1 (IC50=5 nM), MMP-2 (IC50=6 nM), MMP-14 (IC50=9 nM)and MMP-7 (IC50=13 nM).

Tabernanthalog (TBG) is a 5-HT2A agonist. In rodents,Tabernanthalog has been found to promote structural neuroplasticity, reduce alcohol-seeking and heroin-seeking behavior, and produce antidepressant effects.

Resveratrol (SRT 501) is a polyphenolic natural product, a plant antitoxin with antioxidant and chemopreventive activities. Resveratrol has a wide range of targets including COX, SIRT, LOC, etc. Resveratrol induces autophagy and apoptosis.