5 propargylamino 3' azidomethyl dctp

5-Propargylamino-3'-azidomethyl-dCTP, is a nucleoside molecule. It finds utility in DNA synthesis and DNA sequencing.

Methyl 3, 5-dihydroxybenzoate was used in the synthesis of cored dendrimers.

Dmt-2'fluoro-da(bz) amidite is a 2'-deoxy-2'-fluoro-phosphorothioate oligonucleotide with high affinity and specificity for RNA targets and serves as an intermediate in the synthesis of 5'-DMT-3'-phosphoramidite, an antisense compound resistant to nuclease.

3-Amino-1,2,4-triazole (Trapidil impurity B) is an inhibitor of catalase, capable of inducing the compensatory mechanism for hydrogen peroxide detoxification. This mechanism involves increasing the activities of glutathione peroxidase and glutathione reductase.

Methyl 8-(3-octyloxiran-2-yl)octanoate (Methyl 9,10-epoxystearat) is an organic compound containing an epoxy group and an ester group for use in organic synthesis and biochemical experiments.

5-Methylhexan-3-one is a ketone compound widely used in biochemical experiments and drug synthesis research.

3,5-Dinitrosalicylic acid is an aromatic compound. It reacts with reducing sugars and other reducing molecules to form 3-amino-5-nitrosalicylic acid.

Acetylcholine perchlorate is the perchlorate salt of acetylcholine. Acetylcholine, an endogenous neurotransmitter at cholinergic synapses, could amplify the action potential of the sarcolemma following by inducing muscle contractions.

Guanylyl Imidodiphosphate trisodium (Guanosine 5'-[β,γ-imido]triphosphate), a non-hydrolysable GTP analogue, activates ADP-ribosylation factor (ARF) and strongly stimulates adenylate cyclase. It is utilized in protein synthesis studies [1] [2] [3].

Nocardamine is a ferrioxamine siderophore that has been found inStreptomycesand has diverse biological activities.1,2,3,4It chelates iron in a chrome azurol S assay (IC50= 9.9 μM).1Nocardamine inhibitsM. smegmatisandM. bovisbiofilm formation (MIC = 10 μM for both), an effect that can be reversed by iron.2It is cytotoxic to T47D, SK-MEL-5, SK-MEL-28, and RPMI-7951 cancer cells (IC50s = 6, 18, 12, and 14 μM, respectively).3Nocardamine also induces morphological changes in BM-N4 insect cells.4 1.Lopez, J.A.V., Nogawa, T., Futamura, Y., et al.Nocardamin glucuronide, a new member of the ferrioxamine siderophores isolated from the ascamycin-producing strain Streptomyces sp. 80H647J. Antibiot. (Tokyo)72(12)991-995(2019) 2.Ishida, S., Arai, M., Niikawa, H., et al.Inhibitory effect of cyclic trihydroxamate siderophore, desferrioxamine E, on the biofilm formation of Mycobacterium speciesBiol. Pharm. Bull.34(6)917-920(2011) 3.Kalinovskaya, N.I., Romaneko, L.A., Irisawa, T., et al.Marine isolate Citricoccus sp. KMM 3890 as a source of a cyclic siderophore nocardamine with antitumor activityMicrobiol. Res.166(8)654-661(2011) 4.Matsubara, K., Sakuda, S., Tanaka, M., et al.Morphological changes in insect BM-N4 cells induced by nocardamineBiosci. Biotechnol. Biochem.62(10)2049-2051(1998)

Methyl 3-hydroxydecanoate can be used in related research in the field of life sciences. Its product number is T37676 and CAS number is 62675-82-5.

Heneicosapentaenoic Acid (HPA) is a 21:5 ω-3 fatty acid present in trace amounts in the green alga *B. pennata* and in fish oils. Its structure is similar to eicosapentaenoic acid (EPA) but elongated with one carbon at the carboxyl end, placing the first double bond in the δ6 position. HPA is utilized to study the significance of the position of double bonds in ω-3 fatty acids and incorporates into phospholipids and triacylglycerol in vivo as efficiently as EPA and docosahexaenoic acid. It strongly inhibits arachidonic acid synthesis from linoleic acid, is a poor substrate for prostaglandin H synthase (PGHS) (cyclooxygenase) and 5-lipoxygenase, but rapidly inactivates PGHS.

Capsaicin, the chemical that imparts the spicy-hot quality of chili peppers, is produced by the fruits of plants belonging to the Capsicum family. 8-methyl Nonanoic acid is an immediate precursor of capsaicin as well as a by-product of capsaicin degradation.[1] Addition of 5 mM of 8-methyl nonanoic acid significantly increases the yield of capsaicin in both immobilized and freely suspended cells of C. frutescens. [2] Capsaicin has reported antimicrobial properties, however isocapric acid can act as a growth substrate in certain bacterial strains.[3]

Sphingosine-1-phosphate (S1P) is a bioactive lipid that exhibits a broad spectrum of biological activities including cell proliferation, survival, migration, cytoskeletal organization, and morphogenesis. It exerts its activity by binding to five distinct G protein-coupled receptors, S1P1 EDG-1, S1P2 EDG-5, S1P3 EDG-3, S1P4 EDG-6, and S1P5 EDG-8. W140 is an inactive enantiomer of W146, a selective S1P1 antagonist (Ki = 77 nM), that binds to the S1P1 receptor with a Ki of 4.6 μM (2a = W146; 2b = W140 in supplemental material). It exhibits no biological activity in vivo and can therefore serve as an effective control compound for experiments involving W146.

2',3'-Dideoxy-5-iodocytidine, a chemical compound, is employed in gene sequencing and functions as an antibiotic. It exhibits significant efficacy specifically against Mycobacterium.

ddCTP, one of the 2',3'-dideoxyribonucleoside 5'-triphosphates (ddNTPs), functions as a chain-elongating inhibitor of DNA polymerase for DNA sequencing.

5-Propargylamino-3'-azidomethyl-dUTP is a nucleoside molecule utilized in DNA synthesis and sequencing.

Guanosine 5'-diphosphate (GDP) sodium is a nucleoside diphosphate known for activating the adenosine 5'-triphosphate-sensitive K+ channel, serving as a potential iron mobilizer by inhibiting the hepcidin-ferroportin interaction, and modulating the interleukin-6 (IL-6) stat-3 pathway. It is utilized in research on inflammation-related conditions, including anemia of inflammation (AI).

Dideoxythymidine triphosphate trisodium (ddTTP), a 2',3'-dideoxyribonucleoside 5'-triphosphate (ddNTP), functions as a chain-elongation inhibitor of DNA polymerase in DNA sequencing applications [1].

Omega-3 Arachidonic Acid ethyl ester, a rare polyunsaturated fatty acid with limited presence in dietary sources, is crucial for infant growth and development and offers protection against heart disease, blood clots, high blood pressure, and inflammatory and autoimmune disorders. In human platelet membranes, it impedes arachidonyl-CoA synthetase, exhibiting a Ki of 14 μM, and shows similar inhibitory effects on arachidonoyl-CoA synthetase in calf brain extract with an IC50 of roughly 5 μM. The ethyl arachidonate derivative offers enhanced lipophilicity compared to its free acid counterpart.

ddUTP (lithium), at a concentration of 100mM in H20, serves as a nucleotide analog capable of being integrated into DNA, RNA, or other nucleic acids. It is applicable in DNA RNA hybridization experiments including Southern and Northern blots.

cis-13,16,19-Docosatrienoic acid methyl ester is an ester form of docosatrienoic acid, a rare ω-3 fatty acid. This compound is not easily detectable in the normal phospholipid polyunsaturated fatty acid pool and at a concentration of 5 μM, it inhibits the binding of [3H]-LTB4 to porcine neutrophils. The methyl ester form exhibits greater lipid solubility than the free acid, potentially making it more suitable for certain formulations.

19-Iodocholesterol 3-acetate is a biochemical reagent that can be used as a biomaterial for life science related research and as a sulfonylation reagent for organic synthesis and drug discovery.