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Results for "

5α pregnane 3β,6α diol 20 one

" in TargetMol Product Catalog
  • Inhibitors & Agonists
    40
    TargetMol | Inhibitors_Agonists
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    TargetMol | Compound_Libraries
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5α-Pregnane-3β,6α-diol-20-one
T1351821853-11-2
5α-Pregnane-3β,6α-diol-20-one is a mitogenic metabolite derived from progesterone, synthesized by androgen-responsive prostate cancer cells under starvation conditions.
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Staurosporine
CGP 41251, Antibiotic AM-2282, AM-2282
T668062996-74-1
Staurosporine (AM-2282) is a protein kinase inhibitor with ATP-competitive and non-selective inhibitory activity (IC50=6 15 2 3 3000 nM) against PKC, PKA, c-Fgr, phosphorylase kinase and TAOK2. Staurosporine also induces apoptosis.
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(-)-Isopulegol
Fr1420789-79-2
Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH incr
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18β-Glycyrrhetinic acid
Glycyrrhetin, Enoxolone
T0036471-53-4
18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
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Uridine
β-Uridine, Uridin, NSC 20256
T222158-96-8
Uridine (Uridin) is a nucleoside compound, one of the four bases that make up RNA, that replaces thymine in DNA during transcription and pairs with adenine.
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L-Arginine
L-Arg, (S)-(+)-Arginine
T3S036474-79-3
1. L-Arginine (L-Arg) exhibits anti-atherosclerotic effect. 2. L-Arginine and soy enriched diet are effective in prevention of osteoporosis associated with diabetes mellitus. 3. Exogenous L-Arginine could enhance neonate lymphocyte proliferation through an interleukin-2-independent pathway. 4. A combination of oral L-citrulline and L-Arginine effectively and rapidly augments NO-dependent responses at the acute stage.
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alpha-D-glucose
α-D-Glucose, alpha-Glucose, α-Dextrose
T4884492-62-6
alpha-D-glucose (α-Dextrose) is a primary source of energy for living organisms. It is naturally occurring and is found in fruits and other parts of plants in its free state. It is used therapeutically in fluid and nutrient replacement.
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Dipotassium glycyrrhizinate
T566668797-35-3
Dipotassium glycyrrhizinate is an anionic surfactant having anti-allergic and anti-inflammatory activities.
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(-)-Perillaldehyde
T911218031-40-8
(-)-Perillaldehyde shows antibacterial activity.
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7-10 days
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DL-Methionine
Racemethionine, Acimetion
TJO274259-51-8
DL-Methionine (Acimetion) is an amino acid. Amino acids are the building blocks that our bodies use to make proteins. DL-Methionine is found in meat, fish, and dairy products. It plays an important role in the many functions within the body.
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Isoquercetin
3-Glucosylquercetin, Hirsutrin, Isoquercitrin, Quercetin 3-o-glucopyranoside
T5S0754482-35-9
1. Isoquercetin (3-Glucosylquercetin) is a potential stimulator of bone mineralization used for prophylaxis of osteoporotic disorders. 2. Isoquercetin may be as a potential therapeutic agent against neurodegeneration in Parkinson's disease. 3. Isoquercetin is an inhibitor of Wnt β-catenin and may be as a potential novel anti-tumoral agent, such as against human pancreati,liver cancer related to opioid receptors and to the activation of the mitogen-activated protein kinase (MAPK) signalling pathway. .
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(Rac)-Germacrene D
1(10),4(14),5-Germacratriene
T2103237839-63-7
Germacrene D, a natural essential oil, has antioxidant activity and cytotoxicity on tumor cells.
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Ajoene
T3562492285-01-3
Ajoene is a disulfide that has been found inA. sativumand has diverse biological activities, including antibacterial, anticancer, antiplatelet, and antioxidant properties.1,2,3,4It is active against Gram-positive (MICs = 5-160 µg/ml) and Gram-negative bacteria (MICs = 136-200 µg/ml), as well as yeasts (MICs = 10-20 µg/ml).1Ajoene is cytotoxic to mouse melanoma cells (IC50= 18 µM), as well as human colon, lung, mammary, and pancreatic cancer cells (IC50s = 7-41 µM).2It reduces tumor growth in a B16/BL6 mouse model of melanoma when administered at a dose of 25 mg/kg every other day and decreases the number of lung metastases when administered prior to tumor cell inoculation at doses ranging from 1-25 mg/kg. It inhibits ADP- or collagen-induced platelet aggregation in isolated baboon platelets when used at concentrations ranging from 75 to 150 µg/ml and in platelet-rich plasma isolated from baboons when administered at a dose of 25 mg/kg.3Ajoene (25 mg/kg) prevents thrombus formation on damaged arterial walls in heparinized pigs in anin situmodel of thrombogenesis.5It also reduces high-fat diet-induced hepatic steatosis, histopathological markers of liver damage, thiobarbituric acid reactive substances (TBARS) formation, and protein oxidation in a mouse model of non-alcoholic fatty liver disease (NAFLD).4 1.Naganawa, R., Iwata, N., Ishikawa, K., et al.Inhibition of microbial growth by ajoene, a sulfur-containing compound derived from garlicAppl. Environ. Microbiol.62(11)4238-4242(1996) 2.Taylor, P., Noriega, R., Farah, C., et al.Ajoene inhibits both primary tumor growth and metastasis of B16/BL6 melanoma cells in C57BL/6 miceCancer Lett.239(2)298-304(2006) 3.Teranishi, K., Apitz-Castro, R., Robson, S.C., et al.Inhibition of baboon platelet aggregation in vitro and in vivo by the garlic derivative, ajoeneXenotransplantation10(4)374-379(2003) 4.Han, C.Y., Ki, S.H., Kim, Y.W., et al.Ajoene, a stable garlic by-product, inhibits high fat diet-induced hepatic steatosis and oxidative injury through LKB1-dependent AMPK activationAntioxid. Redox Signal.14(2)187-202(2011) 5.Apitz-Castro, R., Badimon, J.J., and Badimon, L.A garlic derivative, ajoene, inhibits platelet deposition on severely damaged vessel wall in an in vivo porcine experimental modelThromb. Res.75(3)243-249(1994)
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Zingibroside R1
Ginsenoside Z-R1
T496280930-74-1
Zingibroside R1 (Ginsenoside Z-R1) has anti-HIV-1 activity.
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Yamogenin
T7529512-06-1
Yamogenin is a diastereomer of diosgenin, which we have identified as the compound responsible for the anti-hyperlipidemic effect of fenugreek.
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(+)-Longifolene
T8110475-20-7
(+)-Longifolene is a naturally occurring.
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7-10 days
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Panaxynol
TN204081203-57-8
Panaxynol is the most potent antiplatelet agent in ginseng and its mechanism of action is chiefly due to the inhibition of thromboxane formation.
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Tetradehydropodophyllotoxin
TN235642123-27-3
Tetradehydropodophyllotoxin (Dehydropodophyllotoxin) has anti-tumor activity.
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Humulene epoxide II
TN422919888-34-7
Humulene epoxide II has antimalarial activity.
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Lappaol C
TN441064855-00-1
Lappaol C has antioxidant and antiaging properties, it may promote the C. elegans longevity and stress resistance through a JNK-1-DAF-16 cascade. Lappaol C also has potential chemosensitizing activity, it may be candidates for developing novel adjuvant an
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