5α cholestane

Cholestane-3,5,6-triol is a useful organic compound for research related to life sciences and the catalog number is T131570.

5β-Cholestane-3α,7α,12α,25-tetrol is a type of bile acid alcohol that activates the G protein-coupled bile acid receptor 1 (GPBAR1), also known as TGR5, in HEK293 cells that express the human receptor, at concentrations between 0.1 to 10 µM. In individuals with cerebrotendinous xanthomatosis (CTX), a progressive metabolic leukodystrophy, levels of this compound are elevated in the blood, feces, and bile.

11β-HSD2-IN-1 (compound CDSN) serves as a potent inhibitor of 11β-HSD2, effectively hindering this enzyme from metabolizing Cholestane-3β,5α,6β-triol (CT) into carcinogenic androstenedione within cells. By inhibiting testosterone biosynthesis, 11β-HSD2-IN-1 suppresses the proliferation of MCF-7 cells. Additionally, this compound exhibits immunological activity and offers protection against viral infections.

6α-Hydroxy-5α-cholestane (6α-OHC) is an oxysterol that promotes superoxide anion production in SK-N-BE cells.

3β,5α,6β-Trihydroxycholestane is a cholesterol metabolite found mainly in animal fats and can modulate SMO activity.3β,5α,6β-Trihydroxycholestane can be used as a biomarker for schizophrenia.

5α-Cholestane belongs to the cholestane steroid class of compounds.

5-alpha-Cholestane-2,2,4,4-d4 is a deuterated compound of 5-alpha-Cholestane. 5-alpha-Cholestane has a CAS number of 481-21-0. 5α-Cholestane belongs to the class of organic compounds known as cholestane steroids.