4methylpiperidine

4-Methylpiperidine is an important nitrogen-containing heterocyclic organic intermediate. It is mainly used in organic synthesis and as an intermediate for drugs, such as serving as a deprotective base for Fmoc in peptide synthesis. It is also used in the preparation of medicines, pesticides, fragrances and functional materials.

NOS-IN-1 (2-Imino-4-methylpiperidine acetate) is a potent and orally active inhibitor of NO synthase (NOS) isoforms. NOS-IN-1 exhibits IC50s of 0.1 μM, 0.2 μM, and 1.1μM for human iNOS (hiNOS), hnNOS and heNOS, respectively.

1-(2,4-Difluorophenyl)-4-methylpiperidine-2,6-dione ,with CAS No. 883023-06-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 1-(2,4-Difluorophenyl)-4-methylpiperidine-2,6-dione provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Benzyl-piperazine-CO-benzothiazole-4-methylpiperidine can be used to alter the lifespan of eukaryotic cells.

'PAG 4'-piperazine-4-methylpiperidine is a specialized cereblon ligand employed in PROTAC research and development. It includes an E3 ligase ligand and a terminal piperidine, allowing for further chemical modifications to produce Protein Degraders with rigid linkers. This compound is part of a suite of functionalized tool molecules used in PROTAC R&D.

Pomalidomide 5'-piperazine-4-methylpiperidine is a compound consisting of an E3 ligase ligand and a linker. It is utilized in PROTAC synthesis, such as in the creation of PROTAC EGFR degrader 13.

(2R,4R)-4-Methylpiperidine-2-carboxylic acid is a useful organic compound for research related to life sciences. The catalog number is T65603 and the CAS number is 74892-81-2.

(2R,4R)-Ethyl 4-methylpiperidine-2-carboxylate is a useful organic compound for research related to life sciences. The catalog number is T66178 and the CAS number is 74892-82-3.

Lenalidomide 5'-piperazine-4-methylpiperidine hydrochloride serves as a specialized cerebellar ligand suitable for PROTAC development. It integrates an E3 ligand with a terminal piperidine, facilitating subsequent chemical reactions. This compound enables the creation of a protein degradant featuring a rigid connector [1].