3hydroxybutyric acid

Butanoic acid is an endogenous human metabolite, an endogenous histone deacetylase (HDAC) inhibitor. The IC50 of HDAC3, HDAC4 and HDAC1 were 2.4 mM, 4.5 mM and 5.3 mM, respectively. 3-Hydroxybutyric acid has the effects of energy metabolism, neuroprotection, anti-inflammatory, and improvement of insulin resistance.

Gamibetal (4-Amino-3-hydroxybutyric Acid) is used as a chiral reagent in the synthesis of antiepileptic and hypotensive drug GABOB and analogues. Also used in the preparation of HIV-1 inhibitors derived from Betulinic Acid (B330250).

(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.

3-Hydroxybutyric acid sodium (β-Hydroxybutyric acid sodium) is a metabolite found in type I diabetic patients that regulates membrane lipids.

4-(p-Biphenylyl)-3-hydroxybutyric acid is a useful organic compound for research related to life sciences and the catalog number is T124405.

(R)-4-Amino-3-hydroxybutyric acid, also known as (R)-GABOB, acts as a modulator of GABA receptors, specifically binding to both GABAA and GABAB receptors and blocking GABA reuptake in rat brain synaptosomes. Additionally, it serves as a GABAC receptor agonist, triggering currents in patch-clamp assays with Xenopus oocytes that express the human receptor. In vivo studies reveal its capability to suppress electrical discharges in the amygdala in cats undergoing N-amidinobenzamide-triggered seizures, indicating its potential therapeutic application in managing seizure disorders.

Poly(3-hydroxybutyric acid-co-3-hydroxyvaleric acid) is a biodegradable polymer used in the formation of nanoparticles for drug delivery.

3-Hydroxybutyric acid-d4 (sodium) is the deuterated form of 3-Hydroxybutyric acid. Also known as β-Hydroxybutyric acid, 3-Hydroxybutyric acid is a metabolite that is elevated in Type I diabetes. It plays a role in regulating the properties of membrane lipids.