3deoxydglycerodgalacto2nonulosonic acid

Sialic acids, commonly present as terminal carbohydrates on glycoconjugates, are essential for a variety of cellular functions including cell adhesion and signal recognition, as well as the formation and progression of tumors. 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid is a deaminated sialic acid that was first identified at the nonreducing ends of oligosialyl chains in rainbow trout egg glycoprotein.[1] It is thought to be a precursor for the biosynthesis of other members of the sialic acid family.[2] 3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid can be used to analyze nonulosonic acid residues in polysialoglycoproteins.[1]

3-Deoxy-D-glycero-D-galacto-2-nonulosonic acid (KDN) sodium is a type of sialic acid. It protects oligo/(poly)sialic acid chains from the impact of non-reducing end exosialidases and plays a role in the activation of salmonid fish eggs. This compound is abundant in fetal umbilical cord red blood cells and human malignant ovarian cancer cells.