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(1)
By Target- CDK
- FGFR(1)
- GSK-3(1)
- VEGFR(1)
- Others(1)
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Results for "
3-methylthienyl-carbonyl-jnj7706621
" in TargetMol Product Catalog- Inhibitors & Agonists1
3-Methylthienyl-carbonyl-JNJ-7706621
T40546443798-09-2
3-Methylthienyl-carbonyl-JNJ-7706621 is a highly potent and selective inhibitor of cyclin-dependent kinase (CDK), showing IC50 values of 6.4 nM for CDK1/cyclin B and 2 nM for CDK2/cyclin A. It also exhibits potent inhibition of GSK-3 (IC50 = 0.041 μM) and moderate inhibition of CDK4, VEGF-R2, and FGF-R2 (IC50 = 0.11 μM, 0.13 μM, and 0.22 μM, respectively), making it significant for cancer research.
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