3-indoleacrylic acid

3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by immune cells.

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.

3-Indoleacrylic acid (Standard) is a reference standard for research and analysis in studies involving 3-Indoleacrylic acid. 3-Indoleacrylic acid is a metabolite of tryptophan produced by Peptostreptococcus species. 3-Indoleacrylic acid has a beneficial effect on intestinal epithelial barrier function and mitigates inflammatory responses by immune cells.

The compound cis-3-Indoleacrylic acid acts as a nematicidal agent and can be isolated from Streptomyces youssoufiensis YMF3.862. It functions as a V-ATPase inhibitor, reducing both the expression and enzymatic activity of V-ATPase. Additionally, cis-3-Indoleacrylic acid causes swelling in Meloidogyne incognita larvae and notable cracking on the cuticle surface [LC50: 16.31 μg/mL]. It also inhibits the accumulation of H+ within nematodes.

trans-3-Indoleacrylic acid is one of the endogenous metabolites that inhibits RSL3-induced ferroptosis and can be used to study colorectal cancer.