3 methylcytidine

3-Methylcytidine as biomarkers of four different types of cancer: lung cancer, gastric cancer, colon cancer, and breast cancer.

3'-Azido-3'-deoxy-5-methylcytidine inhibits HIV-1 reverse transcriptase (EC50 = 0.06 μM) and is an effective inhibitor of xenotropic murine leukemia-related retrovirus [XMRV, CC50 = 43.5 μM].

N4-Benzoyl-3'-O-DMT-2'-O-(2-methoxyethyl)-5-methylcytidine is a cytidine analog that inhibits DNA methyltransferases (such as Zebularine).

3-Methylcytidine (methosulfate), a derivative of cytidine, serves as an internal standard for HPLC and is recognized for its epigenetic modification in tRNA, although its cellular role remains unclear. Research has explored its utility as a cancer biomarker, with findings indicating a notable increase in the urine of breast cancer patients.

3'-Deoxy-3'-alpha-C-methylcytidine is a Nucleoside; Used for nucleoside and nucleic acid modifications.

3'-Deoxy-3'-fluoro-5-methylcytidine is a Nucleoside Derivative - Fluoro-modified nucleoside, 3'-Modified nucleoside, 5-Modified pyrimidine nucleoside.

3'-beta-C-Methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

3'-O-(2-Methoxyethyl)-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

3'-beta-C-Methyl-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

Nucleoside - 3'-O-methyl nucleoside

N4-Benzoyl-2',3'-di-O-(t-butyldimethylsilyl)-5'-O-(4,4'-dimethoxytrityl)-N4-methylcytidine is a nucleoside Derivative - Other modified nucleoside.

Nucleoside Derivatives - Fluoro-modified nucleoside; 2',3'-dideoxy nucleoside; 3'-Modified nucleoside

N4-Benzoyl-3'-O-(2-methoxyethyl)-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

N4-Benzoyl-5'-O-DMT-3'-O-(2-methoxyethyl)-5-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside; Protected nucleoside w NH2 OH open.

N4-Benzoyl-3'-O-methylcytidine is a Nucleoside Derivative - 3'-Modified nucleoside.

5-Aza-3'-beta-methylcytidine (catalog number: TNU1593) is a valuable organic compound for life sciences research.

N4-Benzoyl-3'-O-(4,4'-dimethoxytrityl)-2'-O-(2-methoxyethyl)-5-methylcytidine is a useful organic compound for research related to life sciences and the catalog number is TNU1602.

N4-Benzoyl-3'-O-(4,4'-dimethoxy trityl)-2'-O-(2-methoxyethyl)-5-methylcytidine-5'-CED phosphoramidite is a Nucleoside Phosphoramidite.

Nucleoside Derivatives - Xylo-nucleosides, Fluoro-modified nucleosides

Sorafenib (Bay 43-9006) is a multikinase inhibitor that targets Raf-1, B-Raf, VEGFR2, VEGFR3, VEGFR4, PDGFRβ, FLT3, c-Kit, and others (IC50=6 22 90 15 20 20 57 58 nM) with oral activity. It exhibits antitumor properties and can induce autophagy, apoptosis, and agonistic iron death.

Gemcitabine (LY188011) is a synthetic cytosine nucleoside derivative and an inhibitor of DNA synthesis. Gemcitabine has antitumor and antimetabolic activities. Gemcitabine induces autophagy and apoptosis.

Cyclosporin A is a naturally occurring cyclic polypeptide that is the active metabolite of a fungus. Cyclosporin A is an immunosuppressant that binds to procyclins and inhibits calcineurin (IC50=7 nM).

5-Fluorouracil (5-FU) is a uracil analog and inhibitor of DNA synthesis, exhibiting antitumor activity by affecting pyrimidine synthesis through thymidylate synthase inhibition; it induces apoptosis and autophagy.

IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5 26.3 31.7 μM). IBMX enhances the intracellular cAMP level.