1927-31-7

2'-Deoxyadenosine-5'-triphosphate (Deoxyadenosine 5-triphosphate) (dATP) is a naturally occurring small molecule nucleotide used in cells for DNA synthesis or replication. 2'-Deoxyadenosine-5'-triphosphate (dATP) is a substrate for DNA polymerase. 2'-Deoxyadenosine-5'-triphosphate (dATP) is an inhibitor of RNA through an inactive alpha4beta4 quaternary structure. Deoxyadenosine-5'-triphosphate inhibits RNA through the inactive α4beta4 quaternary structure.2'-Deoxyadenosine-5'-triphosphate has been associated with cardiomyocyte growth.

2'-Deoxyadenosine-5'-triphosphate-D14 dilithium is a deuterium-labeled version of 2'-Deoxyadenosine-5'-triphosphate. This nucleotide, 2'-Deoxyadenosine-5'-triphosphate (T36667) (dATP), is employed in cells for DNA synthesis or replication and acts as a substrate for DNA polymerase.

2'-Deoxyadenosine-5'-triphosphate (dATP) is a purine nucleotide and derivative of the nucleic acid adenosine 5'-triphosphate .1dATP is a substrate for DNA polymerase in the synthesis of DNA.2It is a noncompetitive inhibitor of ribonucleotide reductases, which provides feedback inhibition during DNA synthesis.1dATP has commonly been used in DNA synthesis, sequencing, and labeling in research applications.3,4dATP accumulates in adenosine deaminase deficiency, a disorder characterized by mutations in the gene for adenosine deaminase, the enzyme that catalyzes the deamination of adenosine and deoxyadenosine.5 1.Berg, J.M., Tymoczko, J.L., and Stryer, L.Key steps in nucleotide biosynthesis are regulated by feedback inhibitionBiochemistry(2002) 2.Berg, J.M., Tymoczko, J.L., and Stryer, L.DNA is replicated by polymerases that take instructions from templatesBiochemistry(2002) 3.Cadwell, R.C., and Joyce, G.F.Randomization of genes by PCR mutagenesisPCR Methods Appl.2(1)28-33(1992) 4.Steffens, D.L., Jang, G.Y., Sutter, S.L., et al.An infrared fluorescent dATP for labeling DNAGenome Res.5(4)393-399(1995) 5.Flinn, A.M., and Gennery, A.R.Adenosine deaminase deficiency: A reviewOrphanet J. Rare Dis.13(1)65(2018)

2'-Deoxyadenosine-5'-triphosphate-15N5 dilithium is a version of 2'-Deoxyadenosine-5'-triphosphate dilithium (T36667) that is labeled with nitrogen-15 (15N). This nucleotide, 2'-Deoxyadenosine-5'-triphosphate (dATP), plays a crucial role in cellular processes as it is utilized in DNA synthesis or replication. Additionally, 2'-Deoxyadenosine-5'-triphosphate (dATP) serves as a substrate for DNA polymerase.

2'-Deoxyadenosine-5'-triphosphate-13C10,15N5 dilithium is the isotope-labeled form of 2'-Deoxyadenosine-5'-triphosphate dilithium (T36667). This nucleotide, 2'-Deoxyadenosine-5'-triphosphate (dATP), plays a critical role in cells for DNA synthesis and replication, serving as a substrate for DNA polymerases.

2'-Deoxyadenosine-5'-triphosphate trisodium (dATP trisodium) is a nucleotide substrate for DNA polymerase, essential for DNA synthesis and replication in cells.

2'-Deoxyadenosine-5'-triphosphate-13C10 dilithium is a 13C-labeled form of 2'-Deoxyadenosine-5'-triphosphate dilithium (T36667). This nucleotide, 2'-Deoxyadenosine-5'-triphosphate (dATP), is utilized in cellular processes for DNA synthesis or replication and serves as a substrate for DNA polymerase.