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1599440-33-1

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Dxd
UNII-OQM5SD32BQ, OQM5SD32BQ, Exatecan derivative for ADC
T11249L1599440-33-1
Dxd (OQM5SD32BQ) is a potent DNA topoisomerase I inhibitor (IC50= 0.31 μM). Dxd was used as a conjugate drug for HER2-targeted ADCs.
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Dxd-D5
T89642
Dxd-D5 isomerase I inhibitor with an IC50 value of 0.31 μM. It serves as the effective payload for the antibody-drug conjugate (ADC) targeting HER2, known as DS-8201a.
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