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152013-26-8

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Des-4-fluorobenzyl Mosapride
Des-p-fluorobenzyl Mosapride
T85292152013-26-8
Des-4-fluorobenzyl Mosapride, the main metabolite of mosapride, acts as a gastroprokinetic agent improving upper gastrointestinal (GI) motility by stimulating the serotonin receptor 4 (5-HT4; EC50= 74.2 nM, in guinea pig ileal longitudinal muscle myenteric plexus). It has been shown to increase colonic motility in dogs, horses, and guinea pigs in vivo. Mosapride, including this metabolite, is utilized in human and veterinary medicine to mitigate post-surgical and Parkinson's-induced constipation.
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35 days
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Des-4-Fluorobenzyl Mosapride-D5
TMIJ-01231246814-79-8
Des-4-Fluorobenzyl Mosapride-D5 is a deuterated compound of Des-4-Fluorobenzyl Mosapride. Des-4-Fluorobenzyl Mosapride (T85292) has a CAS number of 152013-26-8.
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20 days
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