1,3,7-trimethyluric acid

1,3,7-Trimethyluric acid, a purine alkaloid, occurs as a minor metabolite of caffeine in humans. It functions as an antioxidant with the ability to scavenge hydroxyl radicals and offers protective benefits against lipid peroxidation in erythrocyte membranes.

1,3,7-Trimethyluric Acid-D9 is intended for use as an internal standard for the quantification of 1,3,7-Trimethyluric Acid (T19792) by GC- or LC-MS. 1,3,7-Trimethyluric acid is a derivative of uric acid and a metabolite of caffeine. It is formed from caffeine by the cytochrome P450 isoform CYP3A4. 1,3,7-Trimethyluric acid scavenges hydroxyl radicals in a cell-free assay and inhibits t-butyl hydroperoxide-induced lipid peroxidation by 56.5% in isolated human erythrocyte membranes.

1,3,7-Trimethyluric Acid-[13C4,15N3] (Standard) is a reference standard of 1,3,7-Trimethyluric Acid-[13C4,15N3] intended for quantitative analysis, quality control, and related biochemical research applications.