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1(4(4(8oxa3azabicyclo[3.2.1]octan3yl)thieno[3,2d]pyrimidin2yl)phenyl)3cyclopropylurea

" in TargetMol Product Catalog
  • Inhibitors & Agonists
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    TargetMol | Inhibitors_Agonists
mTOR inhibitor 9e
T677041144075-40-0In house
mTOR inhibitor 9e is a selective mTOR inhibitor with IC50 of 0.68nM and 1359nM for mTOR and PI3Kα, respectively.
  • $138
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Palmatine chloride
T271810605-02-4
Palmatine chloride an isoquinoline alkaloid, is an important medicinal herbal extract with diverse pharmacological and biological properties.
  • $39
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TargetMol | Inhibitor Hot
Citronellol
dihydrogeraniol
T3240106-22-9
Citronellol ((±)-β-Citronellol) is used in insect repellents and perfumes and as a mite attractant.
  • $30
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Punicalagin
T392165995-63-3
Punicalagin is a major ellagitannin found in pomegranates that is reported to produce antioxidant, anti-inflammatory, and anticancer effects. It has been shown to prevent high-fat diet-induced obesity-associated accumulation of cardiac triglyceride and ch
  • $30
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Punicalin
T4S171865995-64-4
Punicalin exerts anti-inflammatory, antioxidative, and anti-hepatotoxic activities, it shows inhibitory activity on HIV-1 reverse transcriptase in a dose-dependent manner, with an IC50 of 0.11 microg/ml (0.14 microM).
  • $43
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Dehydrocorydaline
Dehydrocorydalin, 13-Methylpalmatine
T5S235830045-16-0
1. Dehydrocorydaline (13-Methylpalmatine) exerts anti-metastatic potential via suppression of MMPs and Bcl-2 signaling in NSC-LC cells. 2. Dehydrocorydaline stimulates p38 MAPK activation, which can enhance heterodimerization of MyoD and E proteins, thus resulting in MyoD activation and myoblast differentiation. 3. Dehydrocorydaline shows antiplatelet effects, it inhibits thrombin-induced platelet aggregation in a low dose ( IC50= 34.914 ug/mL). 4. Dehydrocorydaline has anti-inflammatory and antinociceptive effects. 5. Dehydrocorydaline inhibits MCF-7 cell proliferation by inducing apoptosis mediated by regulating Bax/Bcl-2, activating caspases as well as cleaving PARP.
  • $52
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Valproic Acid
VPA, Sodium valproate, Depakine, 2-Propylvaleric Acid, 2-Propylpentanoic Acid
T706499-66-1
Valproic Acid (2-Propylpentanoic Acid) is an HDAC inhibitor that suppresses HDAC1 activity and induces HDAC2 degradation, exhibiting oral bioavailability. Valproic Acid activates Notch1 signalling and inhibits the proliferation of small cell lung carcinoma cells, making it applicable for research into epilepsy and bipolar disorder.
  • $50
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Wighteone
Erythrinin B, 6-Isopentenylgenistein
TN525451225-30-0
Wighteone (Erythrinin B) is a small molecule compound derived from Genista ephedroides with potential antifungal and anticancer activity against EGFR L858R/T790M mutant non-small cell lung cancer.
  • $73
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1-PeCSO
S-1-Propenyl-L-cysteine sulfoxide
T100253836-24-6In house
1-PeCSO is isolated from onion or garlic bulbs. It acts as a key compound in garlic greening and reacts with lachrymatory factor synthase.
  • Inquiry Price
8-10 weeks
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Rutin hydrate
Sophorin, Rutoside, Quercetin-3-O-rutinoside
T22417190836-14-7In house
Rutin hydrate (Sophorin), a kind of glycoside, widely exists in many plants including citrus fruit.
  • $29
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1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea
T677001144075-47-7In house
1-(4-(4-(8-oxa-3-azabicyclo[3.2.1]octan-3-yl)thieno[3,2-d]pyrimidin-2-yl)phenyl)-3-(pyridin-4-yl)urea is a useful organic compound for research related to life sciences. The catalog number is T67700 and the CAS number is 1144075-47-7.
    8-10 weeks
    Inquiry
    mTOR inhibitor 9a
    T677051144075-32-0In house
    mTOR inhibitor 9a inhibited the growth of human LNCap cells with an ic50 of 80 nm. 1-methyl-3 -{4-[4-(8-oxa-3-azabicyclo[3.2.1]oct-3-yl)thieno[3,2-d]pyrimidin-2-yl]phenyl}urea may have antitumor activity.
    • $147
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    Ethyl 4-hydroxyphenylacetate
    Fr1241517138-28-2
    Ethyl 4-hydroxyphenylacetate is a selective inhibitor of monoamine oxidase A.
    • $30
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    Compound Fr13655
    Fr136551195-09-1
    Compound Fr13655, with CAS No. 1195-09-1, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr13655 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    • $35
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    α-Terpineol
    Terpineol
    Fr1411598-55-5
    Terpineol possesses antifungal activity against Trichophyton mentagrophytes, it also exhibits strong antimicrobial activity against periodontopathic and cariogenic bacteria. α-Terpineol (Terpineol) shows anticonvulsant, and anti-inflammatory activities, it inhibits the gene expression of the IL-6 receptor.
    • $29
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    (-)-Isopulegol
    Fr1420789-79-2
    Isopulegol has antioxidant, and neuroactive properties. It also has gastroprotective effects induced by isopulegol appear to be mediated, at least in part, by endogenous prostaglandins, K+ATP channel opening and antioxidant proprieties related to GSH incr
    • $29
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    Compound Fr14320
    Fr1432017249-80-8
    Compound Fr14320, with CAS No. 17249-80-8, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound Fr14320 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.
    • $35
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    18β-Glycyrrhetinic acid
    Glycyrrhetin, Enoxolone
    T0036471-53-4
    18β-Glycyrrhetinic acid (Enoxolone) is the major bioactive component of Glycyrrhizae Radix and possesses anti-ulcerative, anti-inflammatory and antiproliferative properties.
    • $29
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    D-Mannitol
    Osmitrol, Mannitol, Mannite
    T041469-65-8
    D-Mannitol (Mannitol) is a diuretic and renal diagnostic aid related to sorbitol. It has little significant energy value as it is largely eliminated from the body before any metabolism can take place. It can be used to treat oliguria associated with kidney failure or other manifestations of inadequate renal function and has been used for determination of glomerular filtration rate. D-Mannitol is also commonly used as a research tool in cell biological studies, usually to control osmolarity.
    • $30
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    γ-Aminobutyric acid
    Piperidic acid, Gamma-aminobutyric acid, 4-Aminobutyric acid, 4-Aminobutanoic acid
    T050856-12-2
    γ-Aminobutyric acid (4-Aminobutyric acid) is the predominant inhibitory neurotransmitter in the central nervous system.
    • $30
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    Myricetin
    Cannabiscetin
    T0579529-44-2
    Myricetin (Cannabiscetin) is a natural flavonoid and MEK1 inhibitor. Myricetin has hypoglycemic, antioxidant, hepatoprotective, anti-tumor and anti-inflammatory activities.
    • $30
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    Lactose
    T058663-42-3
    Lactose is a disaccharide derived from galactose and glucose that is found in milk.
    • $42
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    D-Phenylalanine
    T0689673-06-3
    D-Phenylalanine, a necessary aromatic amino acid, is a precursor of thyroxine, dopamine, melanin, and noradrenaline (norepinephrine).
    • $31
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    Isoliquiritigenin
    Isoliquiritigen, ISL, GU17
    T0725961-29-5
    Isoliquiritigenin (ISL) is a flavonoid natural product that inhibits influenza virus replication (EC50=24.7 μM) and aldose reductase activity (IC50=320 nM). Isoliquiritigenin has antitumor activity.
    • $50
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