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By Target- Antifungal
- Apoptosis(1)
- Cytochromes P450(1)
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By Target By ResearchField- Infection(1)
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Results for "
δ60hscyp51
" in TargetMol Product Catalog- Inhibitors & Agonists2
- Isotope Products1
Tebuconazole
T17022107534-96-3
Tebuconazole is an agricultural azole fungicide. It can also inhibit CYP51 (IC50s: 0.9 and 1.3 μM for Candida albicans CYP51 and truncated Homo sapiens CYP51, respectively).
- $31
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Tebuconazole-d4
TMIT-0493
Tebuconazole-d4 is the deuterium-labeled form of Tebuconazole. Tebuconazole, an orally active triazole fungicide, inhibits CYP51, with IC50 values of 0.9 μM for Candida albicans CYP51 (CaCYP51) and 1.3 μM for the truncated human CYP51 (Δ60HsCYP51). It induces lipid accumulation and oxidative stress in HepG2 cells, reduces viability and proliferation of MAC-T cells, triggers endoplasmic reticulum stress-mediated apoptosis, and increases oxidative stress in MAC-T cells.
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