α-glucosidase-in-22

α-Glucosidase-IN-22 is a selective inhibitor of α-glucosidase (IC50=0.64 μM). α-Glucosidase-IN-22 has antidiabetic activity and has potential in type 2 diabetes (T2DM) studies.

α-Amylase/α-Glucosidase-IN-22 is an inhibitor of α-amylase and α-glucosidase, with IC50 values of 1.71 nM and 10.36 nM, respectively (showing potencies 23.8 times and 5 times that of acarbose). It is applicable in the study of metabolic diseases, such as diabetes.

Gitogenin (Standard) is a reference standard for research and analysis in studies involving Gitogenin. 1. Gitogenin, tigogenin, and solasodine are novel selective inhibitors of UGT1A4, and do not inhibit the activities of major human CYP isoforms. 2. Gitogenin and (25S)-5α-furastan-3β, 22, 26-triol are the inhibitors of enzyme α-glucosidase with IC50 values of 37.2±0.18 and 33.5±0.22 uM, respectively.3. Gitogenin shows moderate stimulation of release activity on growth hormone from rat pituitary cells.