α muricholic acid

α-Muricholic acid is the most abundant primary bile acid in rodents.

Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid . TαMCA is common in rodents but has also been found in small amounts in human serum.

Tauro-ω-muricholic acid sodium (TωMCA sodium) is an analogue of tauro-α-muricholic acid, a bile acid derived from the liver. TωMCA sodium can serve as a serum marker for early onset neonatal sepsis (EOS) and biliary stasis.

α-Muricholic acid (Standard) is a reference standard for research and analysis in studies involving α-Muricholic acid. α-Muricholic acid is the most abundant primary bile acid in rodents.

Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).

β-Muricholic acid (β-MCA) is a murine-specific primary bile acid.[1],[2] Dietary administration of β-MCA reduces HMG-CoA reductase activity in liver microsomes from mice fed a high cholesterol and cholic acid diet.[3] Dietary administration of β-MCA also dissolves 100% of gallstones in a gallstone-susceptible mouse model of diet-induced cholesterol gallstones.[4]

ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.

Tauro-β-muricholic acid (TβMCA), a trihydroxylated bile acid, serves as a competitive and reversible FXR antagonist (IC50 = 40 μM) and demonstrates antiapoptotic effects by preventing bile acid-induced hepatocellular apoptosis and maintaining mitochondrial membrane potential [1][2].

ω-Muricholic Acid-d5 is the deuterated form of ω-Muricholic Acid.

Tauro-β-muricholic acid sodium (Standard) is a reference standard for research and analysis in studies involving Tauro-β-muricholic acid sodium. Tauro-β-muricholic Acid sodium is a endogenous metabolite, is a competitive and reversible antagonist of farnesoid X receptor (FXR)(IC50 of 40 μM).

Tauro-α-muricholic Acid (sodium salt) (Standard) is a reference standard for research and analysis in studies involving Tauro-α-muricholic Acid (sodium salt). Tauro-α-muricholic acid (TαMCA) is an antagonist of the farnesoid X receptor (FXR; IC50 = 28 μM) and a taurine-conjugated form of the murine-specific primary bile acid α-muricholic acid . TαMCA is common in rodents but has also been found in small amounts in human serum.

ω-Muricholic Acid (Standard) is a reference standard for research and analysis in studies involving ω-Muricholic Acid. ω-Muricholic acid (ω-MCA) is a murine-specific secondary bile acid.

β-Muricholic Acid (Standard) is a reference standard for research and analysis in studies involving β-Muricholic Acid. β-Muricholic acid (β-MCA) is a primary bile acid unique to rodents. Administering β-MCA through diet can reduce the activity of HMG-CoA reductase in the liver microsomes of mice fed with high cholesterol and chenodeoxycholic acid diets. Giving β-MCA can also cause 100% of the cholesterol-containing gallstones in the diet-induced gallstone model to dissolve.