T78744 |
IRAK4-IN-24
|
|
98%
|
|
IRAK4-IN-24 (compound 16), a potent IRAK4 inhibitor, exhibits high clearance (Cl) and low oral bioavailability. It is utilized in research pertaining to inflamma...
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T79097 |
PROTAC IRAK4 degrader-8
|
2911615-06-8
|
98%
|
|
PROTAC IRAK4 Degrader-8 (Compound 2) is a PROTAC designed to target IRAK4 with an IC50 of 15.5 nM [1].
|
T79337 |
IRAK4-IN-28
|
2952532-92-0
|
98%
|
|
IRAK4-IN-28 (compound 42), an orally-active IRAK4 inhibitor (IC50=8.9 nM), exhibits strong binding affinity with a Kd of 0.58 nM for the target enzyme. It is uti...
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T79447 |
IRAK4-IN-25
|
|
98%
|
|
IRAK4-IN-25 (compound 38), a potent oral IRAK4 inhibitor (IC50 = 7.3 nM) with low clearance (Cl = 12 mL/min/kg), effectively suppresses pro-inflammatory cytokine...
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T79448 |
IRAK4-IN-26
|
|
98%
|
|
IRAK4-IN-26 (Compound 21), an IRAK4 inhibitor with an IC50 of 6.2 nM, exhibits an oral bioavailability of 21%. It is utilized for the study of inflammatory and a...
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T79485 |
IRAK4-IN-27
|
|
98%
|
|
IRAK4-IN-27 (Compound 22) is a potent and selective IRAK4 inhibitor, demonstrating an IC50 of 8.7 nM. It effectively suppresses cell growth and induces apoptosis...
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T11670 |
IRAK inhibitor 3
|
1012343-93-9
|
98%
|
|
IRAK inhibitor 3 is an interleukin-1 (IL-1) receptor-associated kinase (IRAK) modulator.
|
T9027 |
CA-4948
|
1801344-14-8
|
99.62%
|
|
CA-4948 (Emavusertib) is a potent IRAK4/FLT3 inhibtor. CA-4948 with anti-tumor activity.
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T5354 |
IRAK4-IN-7
|
1801343-74-7
|
99.6%
|
|
IRAK4-IN-7 (CA-4948) is a selective and potent IRAK4 kinase inhibitor with in vivo activity in a TLR4-induced cytokine release model.
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T63388 |
IRAK4-IN-8
|
2033070-97-0
|
99.39%
|
|
IRAK4-IN-8 (VI-177) is an IRAK4 inhibitor for the study of diseases associated with cancer and inflammation.
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T7368 |
IRAK inhibitor 2
|
928333-30-6
|
99.26%
|
|
IRAK inhibitor 2 (IRAK-IN-2) is a potent inhibitor of interleukin 1 receptor-associated kinase 4 (IRAK-4) for the study of inflammation-related diseases.
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T11673 |
IRAK4-IN-4
|
1850276-58-2
|
99.13%
|
|
IRAK4-IN-4 (compound 15) inhibits cyclic GMP-AMP synthase (cGAS) with an IC50 of 2.1 nM.IRAK4-IN-4 is an interleukin-1 receptor–associated kinase 4 (IRAK4) inhib...
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T2822 |
Ginsenoside Rb1
|
41753-43-9
|
99.12%
|
|
Ginsenoside Rb1 (Gypenoside Ⅲ) is part of a class of steroid glycosides; may have properties that inhibit or prevent the growth of tumors.
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T7755 |
Thalidomide 4-fluoride
|
835616-60-9
|
99.12%
|
|
Thalidomide 4-fluoride (E3 ligase Ligand 4) (Cereblon ligand 4) is the Thalidomide-based Cereblon ligand. Thalidomide 4-fluoride can be used in the recruitment o...
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T7035 |
ANTHRAQUINONE-2-CARBOXYLIC ACID
|
117-78-2
|
99.08%
|
|
Anthraquinone-2-carboxylic acid acts as a potent anti-inflammatory and antinociceptive component in vivo, thus contributing to the immune regulatory role of frui...
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T75113 |
GLPG2534
|
2095615-97-5
|
98.89%
|
|
GLPG2534 is an orally active, selective and potent IRAK4 inhibitor with anti-inflammatory activity. GLPG2534 inhibits human and mouse IRAK4 and could be used to ...
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T2457 |
IRAK-1-4 Inhibitor I
|
509093-47-4
|
98.77%
|
|
IRAK-1-4 Inhibitor I is a dual inhibitor of IRAK4 and IRAK1.
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T37076 |
Zabedosertib
|
1931994-81-8
|
98.48%
|
|
Zabedosertib (BAY 1834845) is an inhibitor of IRAK4 with immunomodulatory potential. Zabedosertib protects against acute respiratory distress syndrome, a new stu...
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T73334 |
Larotinib
|
1438072-11-7
|
98.45%
|
|
Larotinib is an orally active, potent, and broad-spectrum tyrosine kinase inhibitor (TKI) with an IC50 of 0.6 nM for EGFR.
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T14367 |
AZ1495
|
2196204-23-4
|
98.36%
|
|
AZ1495 is an oral active inhibitor of Interleukin-1 receptor associated kinase 4 (IRAK4), with IC50 values of 5 nM and 23 nM for IRAK4 and IRAK1, respectively. W...
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