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Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T6403 | Siponimod | BAF-312 | S1P Receptor , LPL Receptor |
BAF312 (Siponimod (BAF-312)), a next-generation S1P receptor modulator, is specific for S1P1 and S1P5 receptors with EC50 of 0.39 nM and 0.98 nM, respectively. The specificity of BAF312 for S1P1 and S1P5 receptors exhibi... | |||
T6561 | Laquinimod | LAQ,ABR-215062 | Apoptosis , Others , NF-κB |
Laquinimod (LAQ) is an effective immunomodulator, which is currently under development in phase III trials for the treatment of multiple sclerosis as an oral therapy. | |||
T22282 | Brr2-IN-3 | Brr2 Inhibitor 9,Brr2 Inhibitor C9 | Others |
Brr2-IN-3 (Brr2 Inhibitor C9) is an allosteric inhibitor of the spliceosomal RNA helicase Brr2. Brr2 is implicated in autosomal-dominant retinitis pigmentosa (a group of progressive retinal degenerative disorders). | |||
T9239 | RS-25344 | PDE | |
RS-25344 is a potent and selective phosphodiesterase (PDE) 4 inhibitor. It inhibits eosinophil chemotaxis and increases progressive motility of spermatozoa in vitro. | |||
T37621 | Ezeprogind disulfate | Beta Amyloid | |
Ezeprogind disulfate is a neurotrophic inducer. Ezeprogind disulfate targets all causes of neurodegeneration including Abeta protein or tau protein. Ezeprogind disulfate can be used for the research of neurological disor... | |||
T72522 | Aurora kinase-IN-1 | ||
Aurora kinase-IN-1, a potent aurora kinase inhibitor, modulates cell cycle progression and induces apoptosis by upregulating G1 cell cycle inhibitory proteins (including p21 and p27), elevating G1 progressive cyclin D1, ... | |||
T39274 | Lumasiran sodium | ||
Lumasiran sodium, an investigational RNA interference (RNAi) therapeutic agent, targets glycolate oxidase to reduce hepatic oxalate production, thereby reducing urinary oxalate excretion. This compound shows promise in a... | |||
T40701 | Ezeprogind | AZP-2006 | |
Ezeprogind (AZP-2006) is an orally active neurotrophic inducer that effectively addresses the underlying factors contributing to neurodegeneration, with a broad scope extending beyond the conventional targets like Abeta ... | |||
T38090 | 3'-sulfo Galactosylsphingosine (ammonium salt) | ||
3'-sulfo Galactosylsphingosine is a form of sulfatide that is lacking the fatty acyl group. It decreases migration and adhesion of B35 neuroblastoma cells and increases cell rounding when used at a concentration of 20 μM... | |||
T35552 | Ganglioside GD3 Mixture (sodium salt) | ||
Ganglioside GD3 is synthesized by the addition of two sialic acid residues to lactosylceramide and can serve as a precursor to the formation of more complex gangliosides by the action of glycosyl- and sialyltransferases.... | |||
T61607 | Laquinimod sodium | ||
Laquinimod (ABR-215062) sodium is a carboxamide derivative administered orally that serves as a powerful immunomodulator, designed to prevent inflammation and neurodegeneration within the central nervous system. This com... | |||
T38187 | 6-Aminophenanthridine | ||
6-Aminophenanthridine is an antiprion agent. It inhibits prion formation in yeast- and mammalian-based screening assays when used alone and, to a greater extent, when used in combination with the α2-adrenergic receptor a... | |||
T83772 | 1-Linoleoyl Lysophosphatidic Acid sodium | 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA | |
1-Linoleoyl lysophosphatidic acid (1-linoleoyl LPA), a glycerophospholipid with linoleic acid at its sn-1 position, acts as an LPA2 receptor agonist and is the predominant LPA form in both mouse and human plasma. This co... |
Cat No. | Product Name | Synonyms | Targets |
---|---|---|---|
T37177 | Norcholic Acid | ||
Norcholic acid is a bile acid and 23-carbon derivative of cholic acid .1Levels of norcholic acid are increased in the urine of patients with liver cirrhosis or cerebrotendinous xanthomatosis (CTX), an inborn error of met... |
Cat No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-03145 | IFN-beta Protein, Human, Recombinant | Human | CHO |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-00831 | IFN-beta Protein, Human, Recombinant (hFc) | Human | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-03467 | IFN-beta Protein, Mouse, Recombinant | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-00539 | GSTA1 Protein, Human, Recombinant (His) | Human | HEK293 |
GSTA1 (Glutathione S-Transferase Alpha 1) is a Protein Coding gene. This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds. Glutathione S-transferases (GSTs) ... | |||
TMPY-02767 | TPP1 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-02153 | TNF beta Protein, Human, Recombinant | Human | E. coli |
Lymphotoxin-alpha, also known as LT-alpha, TNF-beta, Tumor necrosis factor ligand superfamily member 1, LTA TNFSF1, and TNFB, is a secreted protein that belongs to the tumor necrosis factor family. TNF-beta/TNFSF1/Lympho... | |||
TMPY-01400 | CD4 Protein, Human, Recombinant (His) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-01226 | CD4 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPY-05384 | CD4 Protein, Human, Recombinant (hFc) | Human | HEK293 |
T-cell surface glycoprotein CD4, is a single-pass type I membrane protein. CD4 contains three Ig-like C2-type (immunoglobulin-like) domains and one Ig-like V-type (immunoglobulin-like) domain. CD4 is a glycoprotein expre... | |||
TMPH-00583 | Rep Protein, E. coli, Recombinant (GST) | E. coli | E. coli |
Rep helicase is a single-stranded DNA-dependent ATPase involved in DNA replication; it can initiate unwinding at a nick in the DNA. It binds to the single-stranded DNA and acts in a progressive fashion along the DNA in t... | |||
TMPY-04033 | FGF-14 Protein, Canine, Recombinant | Canine | E. coli |
FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve... | |||
TMPY-00368 | ALR Protein, Human, Recombinant (His) | Human | HEK293 |
Alterations in GFER gene have been associated with progressive mitochondrial myopathy, congenital cataracts, hearing loss, developmental delay, lactic acidosis and respiratory chain deficiency in 3 siblings born to consa... | |||
TMPK-00738 | EVA-1/MPZL2 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli... | |||
TMPK-00737 | EVA-1/MPZL2 Protein, Human, Recombinant (hFc) | Human | HEK293 |
MPZL2 encodes myelin protein zero-like 2, an adhesion molecule that mediates epithelial cell-cell interactions in several (developing) tissues.Deleterious variants of Mplz2/MPZL2 affect adhesion of the inner-ear epitheli... | |||
TMPY-02804 | FGF-14 Protein, Human, Recombinant (isoform 1B) | Human | E. coli |
FGF14 is a member of the fibroblast growth factor (FGF) family. Members of this family possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic deve... | |||
TMPK-00191 | PILRA Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Alzheimer's disease (AD) is a neurodegenerative disease characterized by a progressive decline in cognitive performance; Mild Cognitive Impairment (MCI) is instead an objective decline in cognitive performance that does ... | |||
TMPY-02091 | GAD67 Protein, Human, Recombinant (His) | Human | Baculovirus-Insect Cells |
Glutamate decarboxylase 1, also known as 67 kDa glutamic acid decarboxylase, Glutamate decarboxylase 67 kDa isoform and GAD1, is a member of thegroup II decarboxylase family. GAD1 is expressed in benign and malignant ... | |||
TMPK-00928 | VLDLR Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
VLDLR cerebellar hypoplasia (VLDLR-CH) is characterized by non-progressive congenital ataxia that is predominantly truncal and results in delayed ambulation, moderate-to-profound intellectual disability, dysarthria, stra... | |||
TMPK-00029 | Glycophorin A Protein, Human, Recombinant (hFc) | Human | HEK293 |
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes... | |||
TMPY-01924 | HSP60 Protein, Mouse, Recombinant (His) | Mouse | E. coli |
HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins ... | |||
TMPJ-01174 | Cystatin B Protein, Mouse, Recombinant (His) | Mouse | E. coli |
Cystatin B, also called stefin B or liver thiol proteinase inhibitor, is a member of family 1 of the cystatin superfamily. Like Cystatin A, it is an intracellular inhibitor regulating the activities of cysteine proteases... | |||
TMPY-04969 | Allergin 1 Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPY-04963 | Allergin 1 Protein, Human, Recombinant (His) | Human | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPY-05061 | Allergin 1 Protein, Human, Recombinant (hFc) | Human | HEK293 |
MILR1 (Mast Cell Immunoglobulin Like Receptor 1, also known as MCA32) is a Protein Coding gene. It is broadly expressed in the appendix, lymph node, and other tissues. Cell surface immunoreceptor MILR1 has been shown to ... | |||
TMPK-00817 | Glycophorin A Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes... | |||
TMPK-00534 | Glycophorin A Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes... | |||
TMPK-00818 | Glycophorin A Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Granulomatosis with polyangiitis (GPA) presents a wide spectrum of manifestations from the common respiratory symptoms to infrequent neurological and cardiac complications. The challenge in diagnosis and management makes... | |||
TMPJ-00313 | Fumarase Protein, Human, Recombinant | Human | E. coli |
Fumarase is an enzyme that catalyze the reversible hydration/dehydration of fumarate to S-malate and is involved in the tricarboxylic acid or Krebs cycle. Fumarase exists in both form, cytosolic formand N-terminal extend... | |||
TMPY-01876 | HSP60 Protein, Human, Recombinant (His & GST) | Human | E. coli |
HSPD1, also known as HSP60, is a member of the chaperonin family. HSPD1 may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins ... | |||
TMPY-00669 | ARSA Protein, Human, Recombinant (His) | Human | HEK293 |
Arylsulfatase A (ARSA) is synthesized as a 52KDa lysosomal enzyme. It is a member of the sulfatase family that is required for the lysosomal degradation of cerebroside-3-sulfate, a sphingolipid sulfate ester and a major ... | |||
TMPY-00670 | ARSA Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Arylsulfatase A (ARSA) is synthesized as a 52KDa lysosomal enzyme. It is a member of the sulfatase family that is required for the lysosomal degradation of cerebroside-3-sulfate, a sphingolipid sulfate ester and a major ... | |||
TMPY-02003 | FH/Fumarate Hydratase Protein, Human, Recombinant (His) | Human | E. coli |
Fumarate Hydratase (FH) is an enzymatic component of the tricarboxylic acid (TCA) cycle, or Krebs cycle, and catalyzes the formation of L-malate from fumarate. It exists in both a cytosolic form and an N-terminal extende... | |||
TMPY-02456 | IFN-beta Protein, Mouse, Recombinant (hFc) | Mouse | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPY-03828 | IFN-beta Protein, Rhesus, Recombinant (mFc) | Rhesus | HEK293 |
Interferons (IFNs) are natural glycoproteins belonging to the cytokine superfamily and are produced by the cells of the immune system of most vertebrates in response to challenges by foreign agents such as viruses, paras... | |||
TMPJ-00158 | Apolipoprotein A-I/APOA1 Protein, Human, Recombinant | Human | E. coli |
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various... | |||
TMPJ-00828 | Tau-F Protein, Human, Recombinant | Human | E. coli |
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons... | |||
TMPY-05215 | TPP1 Protein, Mouse, Recombinant (His) | Mouse | Baculovirus-Insect Cells |
Tripeptidyl-peptidase 1 (TPP1 / CLN2) is a member of the sedolisin family of serine proteases. The protease functions in the lysosome to cleave N-terminal tripeptides from substrates, and has weaker endopeptidase activit... | |||
TMPY-01852 | CHST3 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
Carbohydrate sulfotransferase 3, also known as Chondroitin 6-O-sulfotransferase 1, Chondroitin 6-sulfotransferase and CHST3, is a single-pass type II membrane protein which belongs to thesulfotransferase 1 family and ... | |||
TMPY-04115 | LAMP2 Protein, Human, Recombinant (His) | Human | HEK293 |
LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. LAMP2, also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selec... | |||
TMPY-03385 | FKBP14 Protein, Human, Recombinant (His) | Human | HEK293 |
FKBP14 belongs to the FK506-binding protein family. It contains 2 EF-hand domains and one PPIase FKBP-type domain. FKBP14 can be detected in the lumen of the endoplasmic reticulum where it is thought to accelerate the fo... | |||
TMPY-02382 | LAMP2 Protein, Mouse, Recombinant (His) | Mouse | HEK293 |
LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. LAMP2, also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selec... | |||
TMPY-03685 | LAMP2 Protein, Cynomolgus, Recombinant (His) | Cynomolgus | HEK293 |
LAMP2 (Lysosomal Associated Membrane Protein 2) is a Protein Coding gene. LAMP2, also known as CD107b (Cluster of Differentiation 107b), is a member of a family of membrane glycoproteins. This glycoprotein provides selec... | |||
TMPY-03554 | GCAP1 Protein, Human, Recombinant | Human | Baculovirus-Insect Cells |
GCAP 1 gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messenger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by ... | |||
TMPY-02752 | SPG21 Protein, Mouse, Recombinant (His & GST) | Mouse | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPY-01057 | SPG21 Protein, Human, Recombinant (GST) | Human | Baculovirus-Insect Cells |
Spastic paraplegia 21 (SPG21), also known as acid Cluster Protein 33 (ACP33) and Mast syndrome protein, is a member of the AB hydrolase superfamily. Human SPG21 is a 38 amino acid residue protein widely expressed in all ... | |||
TMPY-03463 | GCAP1 Protein, Human, Recombinant (His & GST) | Human | Baculovirus-Insect Cells |
GCAP 1 gene plays a role in the recovery of retinal photoreceptors from photobleaching. In the recovery phase, the phototransduction messenger cGMP is replenished by retinal guanylyl cyclase-1 (GC1). GC1 is activated by ... | |||
TMPU-00002 | SOS1-Cat Protein, Human, Recombinant (His) | Human | E. coli |
Defects in SOS1 are the cause of gingival fibromatosis 1 (GGF1) [MIM:135300]; also known as GINGF1. Gingival fibromatosis is a rare overgrowth condition. Defects in SOS1 are the cause of Noonan syndrome type 4 (NS4) [MIM... | |||
TMPJ-01083 | Serpin E2 Protein, Mouse, Recombinant (His) | Mouse | Human Cells |
Serpin E2 is a member of the Serpin superfamily. It is differentially expressed during neuronal differentiation and is able to transform human embryonic kidney cells into neuronlike cells. Its over-expression in mice lea... | |||
TMPY-00131 | Niemann Pick C1/NPC1 Protein, Human, Recombinant (His & FLAG) | Human | HEK293 |
Niemann-Pick C1 (NPC1), a host receptor involved in the envelope glycoprotein (GP)-mediated entry of filoviruses into cells, is believed to be a major determinant of cell susceptibility to filovirus infection. Niemann-Pi... | |||
TMPJ-01034 | TIM Protein, Human, Recombinant (His) | Human | E. coli |
Triose-phosphate isomerase, also named Triose-phosphate isomerase, TPI and TIM, is an enzyme that catalyzes the reversible interconversion of the triose phosphate isomers dihydroxyacetone phosphate and D-glyceraldehyde 3... | |||
------------------------ More ------------------------ |
Cat No. | Product Name | ||
---|---|---|---|
L9810 | Anti-Fibrosis Compound Library | 1180 compounds | |
A unique collection of 1180 potential anti-fibrosis compounds, can be used in HTS and HCS; | |||
L2620 | Anti-Neurodegenerative Disease Compound Library | 2150 compounds | |
A unique collection of 2150 compounds related to neurodegenerative diseases can be used for HTS or HCS; | |||
L9830 | Anti-Parkinson's Disease Compound Library | 908 compounds | |
A unique collection of 908 compounds with anti-PD activities or acting on main drug targets of PD can be used for HTS and HCS. | |||
L9840 | Anti-Alzheimer's Disease Compound Library | 1040 compounds | |
A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS. |